Sleep Capsules Efficacy, Toxicological Experimental Studies

Somnia is a kind of physiological action and the most important condition of keeping health. Somnipathy is a common disease and some diseases'concomitant symptom.Insomnia is a common and non-specific disorder and maybe reported by 40-50% of people at any given time.Causes of insomnia include medical illness, alcohol or drugs, periodic limb movement disorder, sleep apnoea, and psychiatric illness. Without an obvious underlying cause, it is known as primary or psychophysiological.The chemosynthesis sedative-hypnotic is widely applied in the clinic to treat insomnia but those shorten SWS and REMS resulting in producing some side effects, such as dizziness, somnolence, dependence and addiction for longly taking medicine, rebounding phenomenon and abstinence for suddenly withdra-wing medicine.In view of traditional Chinese medicine, the reason of insomnia of people who suffered from it derives from mang reasons such as kidney deficiency, liver deficiency, spleen deficiency and so on. Traditional Chinese medicine has low side effect and curative effect.In this disquisition, Hypnotic capisule was studied by the method of behavior pharmacology, increasing number of mice by sodium pentobarbital, prolonging sleep time of mice by sodium pentobarbital and inhibiting convulsion.The results showed that Hypnotic capisule could inhibit independence activity, increase the duration of sleep time of mice and increase the number of sleep mice and prolong convulsion delitescence caused by strychnine.The results revealed that Hypnotic capisule has effects on sedation and hyphosis and low side effect.