Yellow Dogwood The Pharynx Particles Of Pharmaceutical Research

Chronic pharyngitis is a sort of familiar disease of E.N.T. department, it is pathological change and caused by chronic infection, most of it is the inflammatoin of pharyngal mucosa, the incidence of pharyngitis is high, the symptom of it is pertinacious, it os easy to recur. Though being part pathological changes, it's pathogeny is complex, the holistic adjustive treatment is important.Huangyu Pharyngitis granules is a preparation of pure traditoinal Chinese drug, which can be applied to cure and prevent chronic pharyngitis and chronic puinsy. After clinic application of several years, it is proved to be a good remedial effect and patients reflect that they all like it. Now we are researching this drug according to the national neo-drugs. We are in charge of its technical filtration, compound quality standard's establishment and etc.The optimum are chosen by orthogonal test. Considering the aspect of technical filtration, the compatibility of medicines is easy to deposit, we extract the Coptis solely. Taking the volume of the volatile oil as the detective marker, we decide the optimum process of the volatile oil-extraction, distilling them for 8 hours with 6 times of water after immersing them for 1 hour. And then the volatile oil envoloping process: β-CD:volatile oil(6:l); 40℃ stirring speed:900r/min; stirring time:3h. Taking the content of glycyrrhzic acid and the weight of extract as the maker, the water-extraction process is decided: water decocting for Ih and 2 times with 8 times of water. The ethanol-precipitation optimum process: regulating the density of the solution l:1.5(g:ml), the con centration of ethanol is 70% and the content of Evodiamine is the mader. We study out the quality standard for the Huangyu Pharyngitis granules and make qualitative analysis for Coptis, Magnolia and Erodia by TLC. For the reseach of qualitative analysis we determine the content of Berberine by HPLC. We make sure Huangyu Pharyngitis granules is usrful to pharyngitis. The research works creat a favorable foundation and condition for passing the national new drug examination quickly. It can give more service to all the patients' health and can create more social benefit and economic benefit.