Low-level Lead Exposure On Neonatal And Infant

Objective:We conducted this perspective study to assess effects of low level lead CXPOSIItC on physical growth and development, neurobehavioral development and dynamic change of iron and zinc iii newborn and infant in the first year. Methods: We chose 35 neonates from March to December iii 1998 in our hospital. Pregnant wonic&s blood lead, umbilical cord blood lead level(CBPb) and infants' blood lead level were determined as indicators for lead exposure. Body weight, height, head circumference were measured as effect indicators for physical growth and development. Neurohchavioral scores and Gcsell scale For infant development were determined as effect indicators for mieurobehavioral development. Blood iron and zinc were determined as indicators for dynamic change of iron and zinc in body. All indicators were measured at 0,3,6,9, 12 months. Results: Approximately 11 .5% of the study infants or pregnant women had at least one serial blood lead level of 100PPM or higher. Pregnant women's blood were associated with CBPb. Both of pregnant's blood lead and CBPb were related to current blood lead. Current blood lead was neglect correlated with Zinc at 0,3,9 months, Current blood Zinc was related to iron at 3 months. NBNA scores were correlated with fetal lead exposure. liner correlated ana1yses revealed statistically significant between Gesell and CBPb, pregnant women's blood lead, current blood lead at 3,6,9 months. Prenatal and postnatal lead exposure were unrelated to developmental status in neonate and infant. Conclusion: We concluded that low level lead exposure is associated with an adverse developmental impact on neronate and infant, makes Zinc rearrange.