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Tibetan Wing Grass Chemical Composition And Quality Evaluation Studies

Posted on:2002-08-07Degree:MasterType:Thesis
Country:ChinaCandidate:W J LiFull Text:PDF
GTID:2204360032950604Subject:Pharmacy
Abstract/Summary:PDF Full Text Request
ln order to find out effective component curing rheumatoid arthritis and offer effectivemethods for empoldering Tibetan drug P. hooker1 (C. B. Clarke) Hoeck. and appraise itsquality, we did research from geographical resource distributing. pharmacoIogy'Chemical Constituents and qual ity controlling about Tibetan drug P. hookerl(C. B. Clarke) Hoeck.. And we put forward the thoughts about Tibetan drugs' basicresearch and resource protecting. This research has special socia1 meaning andhi gher methodo1ogica1 mean ing.l. Resource geographicaI distributing invcstigationOn autoptical research, we knew zone distributing of Tibetan drug P. hookerl(C. B. Clarke) Hoeck. locates middle part and east of intersecting mountain insOuthwest and northwest parts in china.z. PharmacologicaI research about Anti-innammation and abirritationWe found differ extractCd ped had obvious ant i-inflammatory and antalgic efftct ion.3. Chemical Constituents researchThree compounds were isolated from P. hooker1 (C. B. Clarke) Hoeck. by columnchromatography, they were e1ucidated by spectral evidence as Oleanolic acid' 6--sitosterol and rivularicin. riVUlaricin is first found out from P. hookerl(C. B. C1arke) Hoeck..4. QuaIity evaluationThe contents of Ursolicacid and Loganin were mensurated by TLC-scaning andHPLC. Contents of saPOnin from different area were aIso mensurated. It is suggested thatofficinal parts limit to overground parts.In view of aIl above, it could make sure that saponins were the Anti-inflammatory andantalgic effective parts of P. hookerl (C. B. C1arke) Hoeck.. Three compounds wereisolated from the plant. QuaIitative standards were established for aPpraising multi-tagetS qualityof the drug. And the scientific thereunders were put fOrward for resource exploitation and raisingqualitative standard study leve1 of Tibetan drug P. hookerl (C. B. Clarke) Hoeck..
Keywords/Search Tags:Tibetan drugs, P.hookerl(C.B.Clarke) Hoeck, Triterpenoid saponin, Rivularicin, Quality, evaluat
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