The First Grass Of The Tibetan Wing Anti-rheumatoid Arthritis, The Role And Mechanism,

Pterocephalus hookeri (C.B.Clarke) Hoeck. is a common used drug in the treatment of arthritis of Tibetan drugs. In the study, we have found out its effective parts, and taken them as our study object to investigate its pharmacological effects and mechanism by means of advanced modem scientific research methods such as: radioimmunoassay x ultraviolet, spectrophotometry, organise culture. The results showed as:1. We have approximately screen out the effiective parts by even design means.2. P. hookeri (C.B.Clarke) Ho'eck. has obvious effects on adjuvant arthritis by inhibiting the production and development of the inflammation, meanwhile it does very well on the animal's model of ache, and it also affects immunity.3. The effects on rheumatoid arthritis do not depend on hypophisis-adrenocortical systym. Its mechanism is directly related to decreasing the release of prostaglanda ? (PGE2), interleukin-l(IL-l^ tumor necrosis factor-α (TNF-α) and Nitric Oxide(NO).