Compound Beads Yellow Cream To Promote Clinical And Experimental Study Of The Anal Wound Healing

According to the theory of traditional Chinese medicine, we used the cream compound ZHUHUANG that can clear away pathogenic heat and promote diuresis and activate the blood circulation and regenerate the tissue to treat the anal postoperative wound healing. All of these studies were carried out both in the clinic and the animal experiments. The clinic studies showed that, treated with the cream compound ZI-IUHUANG, the 40 cases of the low pure anal fistula, after operation, bad been improved significantly in the clinic symptoms (wound aching) and the physical signs, and their wound healing time and speed was significantly shorter / faster than the control, the musk hemorrhoidal basilicon MAYINLONG (P<0.05 or 0.01). The studies also showed the cream compound ZHUHUANG could significantly reduce the bacterium detectable rate of the wound surface, and could also significantly improve the amount of the granulation tissue hydroxy-proline (Hyp) and the rate of macrophage in the wound surface (P<0.05 or 0.01). The animal experiments showed that the cream compound ZHUHUANG could excel-lently treat the bunny抯 back wound with feces pollution, effectively restrain the local infection, quicken the pace of granulation tissue filling and epithelialization, increase the number of granulation tissue fibroblasts and new capillaries, and improve the amount of wound protein and available microelement such as Zn, Fe, Mn, Cu. The studies demonstrated the cream compound ZHUHUANG had the effects superior to basicity Fibroblast Growth Factor (bFGF) at the various aspects ( P <0.05 or 0.01). Moreover, the primary research about the therapeutic mechanism of the cream compound ZHUHUANG were made and how to treat the wound healing in the clinic were also projected.