High Fat Diet On Rat Knee Degenerative Joint Disease, Experimental Research

Objektire:To investigate the damaging effect and mechanism of eating adipose food on degenerative osteoarthritis (DOA) in rats. Methods: The DOA models were made by fixing knee joints on extension position. Giving adipose food to observe the damaging effect on articular cartilage and measure the change of hemorrheolgy, blood-lipid,E2. Pathologic listology were used as evaluated means. Results:E2,HDL-C going down, all the others go upper than controls with the even damaging of articular cartilage. Conclulsion:The results suggest that eating adipose food can induce or aggravate the disorder of articular cartilage...