Experimental Study Of Gengnianle The Treatment Of Menopausal Syndrome

Climacteric Syndrome (C 5) is a kind of common and recurrent disease clinically. On the basis of T C M theory and clinical experience of many years, professor Wu Gaoyuan pointed out that "kidney-asthenia and liver depression, impairment of chong and ren channels"is the main pathogenesis of C S. Then, She proposed the "nourish the kidney and soothe the liver, invigorate Chong and ren channels"treatment principle. According to this principle, "Geng Nian Le"was made to treat C S and acquired a good curative effect. This thesis went a step further to demonstrate its curative effect and reveal its mechanism of action through experimental research. The results showed that"Geng Nian Le"can reduce the serum FSH and LH level of menopausal rats, raise their β-EP level of hypothalamus and serum while improve their ER level of uterus, and then regulate the function of hypothalamus-hypophysis-ovary-uterus axis. It also can make estrogen regulate immune function through improving ER level of spleen. Thus, the Neuroendocrine-immune Network will be in stable state.