| Objective:To study the clinical efficacy and safety of Bacillus Licheniformis Capsules combined with Traditional Chinese Medicine decoction in patients with ulcerative colitis (UC).Methods:Cases were from the March 2009～September 2010 the General Hospital of Shenyang Military Region during the period of Traditional Chinese Medicine treated 40 patients with chronic relapsing UC patients,Society of Digestive collaborative group developed the diagnostic criteria.Excel software applicationgs were randomly divided into experimental and control groups ,each of 20cases: trial group ( n = 20) and control group ( n = 20). The patients in the trial group were given Bacillus Licheniformis Capsules (500mg, 3 times daily) combined with Traditional Chinese Medicine decoction , and those in the control group were given Traditional Chinese Medicine decoction only for 8 weeks. Clinical effects and safety were compared between two groups.Results:After treatment, there were no significant differences in the overall clinical efficacy, relief of clinical symptoms, remission in colonoscopy between the two groups ( P > 0.05). The score of main symptom of trial group's lower than control group's( P <0.05). The follow - up from sixmonths to one year showed there were 2 cases of relapse in the trial group while 8 cases of relapse in the control group.Conclusion :Bacillus Licheniformis Capsules combined with Traditional Chinese Medicine decoction is faster than Traditional Chinese Medicine decoction only on control symptom of UC and could diminish the recurrence rate as well. |
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