Clearing Heat And Dampness Of The Efficacy Of Newly Diagnosed Type 2 Diabetes Damp-heat Syndrome Observed

Objective:To evaluate the effect of Chinese herbal medicine (Xiao keqing decoction )united short-term continuous subcutaneous insulin infusion (CSII) treatment on symptomatology of Traditional Chinese Medicine, fasting blood glucose (FBG) ,postprandial 2 hours blood glucose (P2hBG) ,total cholesterol (TC) ,triglyceride (TG) and C reactive protein (CRP) in newly diagnosed type 2 diabetic patients with damp-heat encumbering the spleen. The results would provide some new ideas and some evidences to guide the clinical treatment of T2DM.Method:Sixty-two patients newly diagnosed T2DM with dampness-heat encumbering the spleen had been in Endocrinology Department of Affiliated Hospital Liaoning Univercity of Chinese Medicine as investigation objects.They were randomly divided into treatment and control group. The 43 patients (as treatment group) treated with CSII combined TCM (Xiao keqing decoction )treatment and the other 19 patients (as control group) only CSII treatment. The study observed the changes of symptomatology of TCM before and after,and also observed changes of the FBG ,P2hBG ,TC,TG and CRP.Results:1.After the treatment, the TCM diabetes symptoms of treatment group improved obviously than the control did, the two groups of total effectiveness respectively were 95.35% and 73.68%, and the comparison between groups (P = 0.009 < 0.01) had remarkably statistical significance.2. After the treatment, the two groups symptoms both had been more improvement than before .But comparing the two groups,these symptoms were no statistical significance (P>0.05) , including thirsty to drink , frequent urination and burnout fatigue .While constipation, insomnia ,abdominal fullness and distention, hand-body tired and heavy, these symptoms between the two groups had statistical significance(P<0.05).The total integral of symptomatology of TCM both obviously decreased.And comparing the two groups ,there was statistical significance (P=0.025<0.05).3. The blood glucose of the two groups all had obviously decreased,but comparing the two groups ,there was no statistical significance (p>0.05).The blood fat and CRP also had some decreased,but comparing the two groups there was no statistical significance either.Conclusion:After 2 weeks CSII intensive therapy, even the blood glucose of the diabetes patients reaches the standards while the syndromes of TCM still exist and need some TCM treatment.After 2 weeks CSII the symptoms of treatment group ,CSII combined Chinese medicine(Xiao keqing decoction ),improved obviously than the control did ,but still not disappeared completely and still needed further herbal treatment.