Oral Medicinal Activated Charcoal (ai Xite) To Improve The Study Of Hemodialysis Patients With Serum Phosphorus And Ipth And Chinese Medicine Syndrome Indicators

Clinical Study of the Activated Charcoal Pills in Treating Hyperphosphatemia and Hyperparathyroidism of Hemodialysis PatientsOBJECTChronic renal failure (CRF) is a part of the process of chronic.renal failure(CRF), applying to the course of continuing significant irreversible reduction in nephron number, which leads to the glomerulus functional incapacitation in filtration ability. The dispiriting term end-stage renal-disease represents a stage of the accumulation of toxins, fluid, and electrolytes normally excreted by the kidneys results in the urenia stage, leading the body to death unless the toxins are removed using dialysis or kidney transplantation. Meanwhile, during the stage 5 chronic kidney disease or even earlier periods, there undergoes a series of maladjustments in endocrine system, including the communications of hyperphosphatemia and hypercalcinemia, and the recent epidemiologic evidence strongly give a support to the associations among hyperphosphatemia, higher level of parathyroid glands and the increased cardiovascular mortality, which may make a expedite the decrease of the quality of life maintenance.This research will research on the cases in hemodialysis suffering from the hyperphosphatemia and higher level of parathormone by database analyzing based on the changes in relevant biomedical indicators and the Chinese Medicine syndromes scoring, to observe the possible effectiveness of activated charcoal preparations on the potential usage in toxins absorptions of serum phosphate and the syndrome differentiations in Chinese medicine.METHODCharacter:single center observation with self-compared cases accorded with the entrance standard of the research; Medicine:Activated charcoal pills (Ai Xi Te in pinyin); Observation period:12 weeks; Compared the parameters differentiations of the serum toxins, along with phosphate, parathormone, and the scores of Chinese syndromes. Data statistics:Spss version in 17.0.RESULTS 1. Analysis of the date showed a significant decrease in the amount of serum phosphate and parathormone (P<0.05).2. Analysis of the data indicated that there lies no evident differentiations between the parameters of blood calcium and calcium*phosphate before and after the treatment (P>0.05).3. By scoring the Chinese syndrome of the cases, there was no clear evidence proving the syndrome alternatives;4. There was no patent avail in improving the uremia toxins absorption and degradation by activated charcoal.CONCLUSIONThis clinical study demonstrated that the activated charcoal may have potency in assistance of controlling the level of serum phosphate, indirectly lowering the amount of parathormone. It gained a therapeutic effort for the practicable treatments in regulating hyperphosphatemia. The curative effect in long-range still requires more clinical evidence by observations..