The Acute Phase Of Stroke Disease In Patients With Hypertension And Non-hypertension Group, Tcm Syndromes Comparative Study To

Stroke has some characteristics of high morbidity, disability and mortality. With the aging of the population, its incidence increases year by year. Its disability is up to 75%. The third survey of cause of death was published in 2008. it said that stroke was as the first cause of death in China. Mood disorders induced by stroke, such as anxiety, depression and vascular dementia induced by recurrent stroke get more and more concerns. Therefore, reasonable and effective treatments to the acute stroke patients will affect to the prognosis and quality of life greatly. The treatments of western medicine are anti-platelet aggregation, anticoagulation, thrombolytic, stroke units and only other ways to symptomatic treatment. As the complex pathogenesis and clinical symptoms of stroke, the treatments must be individualized and the staggered. Chinese medicine's advantages in the treatment of the disease are especially prominent. Hypertension is not only a risk factor for stoke, but also affects the development of stroke, the result and evolution of Chinese Medicine Syndromes. At present evolution of Chinese Medicine Syndromes of stroke patients with hypertension still lacks big sample clinical observations.Objective:Discuss evolution of Chinese Medicine Syndromes and neurological impairment of acute stroke patients with hypertension and acute stroke patients without hypertension, contrast differences between two groups.Methods:A prospective study of the subject method, the structured, standardized clinical data collection platform support, use the "clinical diagnosis and treatment of stroke patients dialectical law mining and verification of the program of treatment" cases,63 cases of Observation Records acute stroke patients clinical diagnostic messages for dynamic acquisition, with diagnostic criteria for hypertension 63 patients were divided into non-hypertension group and hypertension group, collection points:1,2,3,7,10,14 days after admission. In addition, neurological impairment be evaluated by the U.S. National Institutes of Health Stroke Scale (NIHSS). Finally using the SPSS 13.0 software on the clinical data collected for statistical analysis.Results:①Syndrome elements of acute stroke,mainly phlegm syndrome,hot syndrome and wind syndrome. With the progression of the disease, it showed that wind syndrome was gradually decreased. However,phlegm syndrome was dominant throughout the course throughout. ②Contrasting syndrome elements between the two groups it showed that on the tenth day, scores of yinxu in non-hypertension group increased significantly more than hypertension group, with statistical significance, on the fourteenth day, scores of xueyu in hypertension group increased significantly more than non-hypertension group, with statistical significance.③Contrasting syndrome elements on those six periods it showed that from the first day to the fourteenth day of admission, in the two group, the frequency distribution of wind gradually reduced, with statistical significance.In hypertension group, from the first day to the fourteenth day of admission, scores of wind, hot and phlegm gradually reduced, but scores of xueyu gradually increased, with statistical significance.In non-hypertension group, from the first day to the fourteenth day of admission, scores of wind,hot and phlegm gradually reduced,but scores of yinxu gradually increased, with statistical significance.④In hypertension group, on the first day five-card combinations were the most, followed by six-card combinations, four-card combinations. Within five-card combinations, the rate of hot+ phlegm + xueyu+qixu+yinxu was the highest. On the seventh day four-card combinations were the most, followed by five-card combinations, six-card combinations. Within four-card combinations, the rate of hot+ phlegm + xueyu+ yinxu was the highest. On the fourteenth day five-card combinations were the most, followed by four-card combinations three-card combinations. Within five-card combinations, the rate of hot+ phlegm + xueyu+qixu+yinxu were the highest;In non-hypertension group, on the first day five-card combinations were the most, followed by six-card combinations four-card combinations. Within five-card combinations, the rates of wind +hot+ phlegm +qixu+yinxu and hot+ phlegm + xueyu+qixu+yinxu were the highest. On the seventh day five-card combinations were the most, followed by four-card combinations, three-card combinations. Within five-card combinations, the rate of hot+ phlegm + xueyu+qixu+yinxu was the highest. On the fourteenth day five-card combinations were the most, followed by four-card combinations three-card combinations. Within five-card combinations, the rate of hot+ phlegm + xueyu+qixu+yinxu was the highest.⑤On the five periods, scores of NIHSS between the two group had no significant differences. In hypertension group,on the first day of admission NIHSS scores were high, on the second day it were higher, on the third day it started to reduce, from this moment the scores gradually reduced, with statistical significance. In non-hypertension group, on the first day of admission NIHSS scores were high, on the second day it were higher, on the third day and the seventh day it increased continuously, on the fourteenth day it clearly reduced, with statistical significance.