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Integrative Treatment Of Metastatic Breast Cancer Clinical Research

Posted on:2012-09-28Degree:MasterType:Thesis
Country:ChinaCandidate:Q Q ZhangFull Text:PDF
GTID:2204330335458882Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
This essay consists of two parts:Two literature reviews and clinical research.Two literature review:the first review discusses applications to metastatic breast cancer. First, The characteristic of metastatic breast cancer is that heathy-qi deficient is the foundation, should treated with strengthening healthy-qi. Then represent treating with Chinese medicine by differentiation of metastatic parts, mainly include bone metastasis, lung metastasis, liver metastasis and so on. The third, Mainly discuss how to improve the life quality of advanced breast cancer, in terms of improving insomnion, depression, pain, anorexia and so on. The second literature review retrospect the chemotherapy of advanced breast cancer, mainly introduce the indications of chemotherapy, the choose methods and principles to chemotherapy, The common use and the latest new chemotherapy regimens include sigle and combination regimens,and target drugs and their new trails passed by FDA.Clinical reseach:Objective:To investigate that combination of Chinese and westen medicine can prolong the RR and TTP. Method:We collect the metastatic breast cancer patients who are hospitalized in the oncology, of China-Japan friendship hospital.We investigate the median overall survival of Chinese-west medicine combination group(died group) is 38.5 months(from 8 to 108 months), chinese-west medicine group (include died and not died) has 59 patients, median TTP is 15 months (4 to 65 months). The west medicine group (died group) has 9 patients, the shortest OS is 2 months, the longest is 9 months, the median overall surviaval is 5 months. Compare to literature,The Chinese-west medicine combination group have a longer OS and TTP. OS of Chinese-west, medicine group and west medicine group have obvious differentiation(P<0.05). Conclusion: Combination of Chinese and west medicine can prolong the OS and TTP.
Keywords/Search Tags:metastatic breast cancer, overal survival, combination of Chinese and westen medicine, OS.TTP
PDF Full Text Request
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