| The IGT Public is the most important public of high risk of type 2 diabetes mellitus, It is significant of the IGT intervention, the IGT stage is the vital occasion of prevention of type 2 diabetes mellitus, the IGT intervention is the important method of Prevention of type 2 diabetes mellitus. According to the data from World Health Organization (WHO) and International Diabetes Federation (IDF) in 1999, there are about 130 million patients with DM around the world. Diabetes are the severely impair human health global popular high morbidity, it sustained growth's epidemiology tendency has become the serious public health question, therefore has become the key point which regarding diabetes early time's intervention treatment the global medical affairs staff pay attention. Impaired glucose tolerance (IGT) is the early stage of type 2 diabetes, and tends to increase the risk for development of diabetes. Impaired glucose regulation (IGR) have three clinical types:impaired fasting glucose (IFG), impaired glucose tolerance (IGT), combination of IFG and IGT. And the IGT crowd is the most important diabetes dangerous crowd, but the IGT stage also has high reversibility, therefore the IGT stage's intervention prevents diabetes important opportunity. The IGT diagnosis standard was in 1999 the World Health Organization and the international diabetes alliance diabetes Expert board official announcement diagnosis standard:FPG<7.0mmol/L (126mg/dl),2hPG≥7.8mmol/L(140mg/dl)and<11. lmmol/L (200mg/dl).IGT is called Pi Dan in Chinese Medicine which is not equal to Xiao Ke and management of this disease also has several features of its own. The IGT intervention by Chinese Medicine has few side-effect, low-price and well-compliancy, it can remarkably improve insulin tolerance, protect (3 cell of pancreas, evidently increase the quality of life. Clinical observation shows that patients in the phase of IGT mostly present with insufficiency of the spleen. And treatment based on spleen usually could gain effects in various degrees. This Paper theoretically and clinically reviews the study on treatment of impaired glucose tolerance by regulating spleen with Chinese Medicine.This thesis discusses the progress of traditional Chinese and modern medical researches on Impaired Glucose Tolerance and the clinical intervention study of the method of yunpi on patients with impaired glucose tolerance.In the first part of the thesis, a summary is made on the epidemiology, dangerous factors, pathogenesis, and adverse effect to other systems and inter-vention study of Impaired Glucose Tolerance in modern medicine in recent years. At present thought that obese, the food habit, the life styles and so on are the IGT most main cause of disease and the hazard factor.IR andβcell dysfunction are the most important pathogenesis of IGT through most of the scholars. The researches on Impaired Glucose Tolerance using Traditional Chinese medicine include theoretic and clinical studies. Most doctors think the basic pathogenesis of IGT is asthenia in origin and sthenia in superficiality. The asthenia in origin includes asthenia of qi and blood, yin and yang, and five viscerals. The sthenia in superficiality includes stagnated blood, dampness, and turbid toxin. The third part introduced the awareness of the Chinese medicine about the dissection structure and the function of the spleen, the. relationship between insulin resistance and spleen, the exposition of "pi xu zhi xiao"from ancient physicians. The thes is also includes:a systemic comparison to review the progress in the past ten years, a simple analysis on the problem and shortages of the researches, and a suggestion on the future direction.This article is also combined with the clinical experiences of doctor zhouying. Zhouying has always been engaged in clinical work and clinical teaching of TCM after he has graduated from BUCM in 1983, and has made grest success in medical work, teaching and research. Zhouying pays attention to the influence of dietary irregularities as well as emotions and mind disorder in the pathogenesis of IGT. He emphasize that definit quantitative determination based on definit nature of disease, chose exactly therapy according to every person's constitution and different period. He medicates herbal drugs with cold-warming method, combination of move and quiescent. A better curative effect can be obtained in treating IGT of TCM, with exactly syndrome differentiation, the definite pathogenesis, the modern treating methods and pharmacological research. Under the regard of pattern identi-fication, Zhouying has got good clinical curative effect through theraping patients with IGT in herbal drugs and Chinese formulated products together. The majority of patient's clinical symptoms are improved, ahd their fasting blood glucose is declined after treating by doctor zhouying. |