Clinical Research Of The Relation Between Type 2 Diabetes And Mild Cognitive Impairment

Objective:To investigate influence factors of mild cognitive impairment and analysis risk factors of the diabetic mild cognitive Impairment. Methods:1. Case-control study :70 cases of Type 2 Diabetics and 51 cases of nomal cases were divided into the MCI group and the normal cogonitive function group. multiple factor logistic regression analysis were conducted to analysis the impact factors to affect the cognitive impairment. 2. 70 cases of Type 2 Diabetics were divided into the MCI group and the normal cogonitive function group. Single and multiple factor logistic regression analysis were conduct to analysis the impact factors to affect the diabetic cognitive impairment . t-test, x2 test, rank sum test and logistic regression analysis were conduct. Results:1. Multiple factor logistic regression analysis showed that Type 2 Diabetics (OR=6.548,P=0.000)and Systolic blood pressure (OR=3.029,P=0.005)were the influence factors for MCI, and educational background (OR=0.431,P=0.000) was the protective factor of MCI. 2. Multivariate analysis Logistic demonstrated that controlling over the blood suga(rHbA1c)(OR=1.416,P=0.017)and microangiopathy (OR=2.336,P=0.009)were the influencing factors for MCI, educational background (OR=0.502 , P=0.026) was the protective factor of MCI. Conclusions:1. controlling over the blood sugar and blood pressue are beneficial to improve the cognitive function of the aged people. These factors coordinating with the aging course cause ebbing of the cognitive. 2. Type 2 Diabetics is an important factor that influence occurrence, development and result of the mild cognitive impairment, which is prone to be intensified by the microangiopathy of diabetes disease course and aggravation of the controling over blood sugar.