Effects Of Shenmai Injection Combined With The Taxinol And Platinol (tp) In The Treatment Of Ovarian Cancer

ObjectiveTo research the curative effect and side effect of Shenmai injection plus TP chems for treating late-stage ovarian cancer.MethodsThe patients of 60 ovarian cancer divided equally into Shenmai group and control group. All patients were given TP chems keep on six times of therapy. Before the chems, the patients were taken dexamethasone 20 mg orally, intravenous injection of benzhydramine 50 mg and ranitidine 50 mg. Before the three days of chems, the Shenmai group was given Shenmai injection 50ml, continued 10 days, and gave chems at the fourth day. Before and after treatment, T-cell subpopulation, clinical effects and side effects were observed.Results1. Before and after treatment, The CD3, CD4 and CD8 of Shenmai group had no significant change (P>0.05). The control group had significantly decrease (P<0.05).2. The effective rate in Shenmai group was 70.0%, compared with the control group 63.3% had no statistical significance (P>0.05).3. The score of Karnofsky, The before and after of treatment, the Shenmai group had no significant change (P>0.05). The pretherapy of control group 77.6±5.0 had descent compared with post-treatment 61.2±3.7 (P<0.05).4. The incidence rate of side effects had significant statistical significance (P<0.05) between two groups. ConclusionShenmai injection combined with TP is effective in treatment of patients with late-stage ovarian cancer, and deserve to generalization of clinical application.