| Objective: Reviewed the studies concerned the inhibition function of patients of Obsessive-Compulsive Disorder (OCD) and tried to figure out the possible underlying inhibitory function disorder. Employed the paradigm of inhibition of return to investigate the inhibition function of OCD patients.Method: Employed the paradigm used by Zhou Jianzhong, which randomly cued 1 to 4 successive locations circle around the centre and required subjects to press the button when target stimulus appeared. Subjects were 16 OCD patients and 16 gender and age matched normal participants. Their obsessive-compulsive symptoms were assessed by OC subscale of SCL-90, Pauda Inventory, Modified Madusley Obsessive-Compulsive Inventory. Depression and state-trait anxiety were measured by Beck Depression Inventory, State-Trait Anxiety Inventory.Result: Unable to observe prolonged reaction time in the cued location when only one periphery location was cued among OCD patients and the prolonged effect were observed in normal group. When the cued locations were up to four, both the patients group and normal control exhibited the capacity of IOR in the last 3 cued locations. A comparison of IOR effect among patients and normal control showed that OCD patients' IOR effect was weaker than normal. When number of cued locations was 2 or more, the correlation of some OC scales results and the reaction time reached significant.Conclusion: Present study found weaken IOR effect when only one location was cued in OCD patients which partially replicated previous researches. As the number of cued locations increased, OCD patients exhibited the same span but weaken IOR effect compared with normal controls. |
