| Chronic Obstructive Pulmonary Disease is one kind of diseases that can be prevented and treated, it has the characteristic of airflow limitation. Which is not completely reversible and progressive development, and to smoke cigarettes with lung, the harmful gas such as the abnormal or harmful granules inflammation. According to the World Health Organization (WHO), in 2005, more than 600 million people worldwide are sick with COPD, including 80 million cases of moderate and severe COPD ,and 3 million patients died of it, COPD become the fourth leading cause of death in the world. COPD severely affects the labor and viability of patients, about 24～63 percent of patients with COPD have the significant and evolutionary weight loss in their natural course, "syndrome of cardiac cachexia" even happen in serious cases.Because of the increasing of the body's energy consumption, the obstacle of gastrointestinal digestion and absorption function, the decrease of the nutrients intake, the increase of catabolism,malnutrition happen in COPD patients. That may have serious effects on body. Research shows the incidence rate of malnutrition in COPD patients amounts to 25% ~ 65%, along with the development of illness, once respiratory failure appears can accentuate further malnutrition. Malnutrition is an independent risk factor of poor prognosis of patients with COPD.The incidence rate in patients with COPD amounts to 50% of the nutrition state reflects human measurement, biochemical and immune abnormalities. Appears as that the human measure figures, biochemical criterion and the immunological indexes that reflect the performance of nutritional status are abnormal. Malnutrition caused the increase of hospitalization expenses and length of stays and overburden the patients. COPD patients with malnutrition have poor prognosis, the mean survival time is expected only 2.9 years, combined with acute respiratory failure patients, the mean survival time will shorten further. Because of the relationship of the extent of malnutrition and airflow obstruction, and the tendency of acute respiratory failure and death, nutritional status is regarded as an important prognostic indicators. This shows that it is important to get nutritional assessment exactly and reasonably. Early detection and treatment of malnutrition is of great significance in improving the quality of patients′life.Objective: To investigate the nutritional status of patients with COPD, analyze the biochemical criterion, blood gas analysis, complication, mortality, utilization rate of mechanical ventilation, the impact of hospital stay and hospitalization expenses, to offer evidence to enhance the nutritional management of patients with COPD, in order to reduce the number of fits.Methods: One hundred and forty-two patients with COPD delivered from Oct.2009 to Apr.2010 at the hospital were selected. With the method of MNA-SF, they had been taken nutrition evaluation. And eight indexes were taken in the meanwhile, such as BMI,biochemical indexes,blood gas analysis and so on. In accordance with the MNA-SF,COPD patients were divided into two groups:malnourished patients and well-nourished patients. Then analysis the indexes between them.Results:There are 52 well-nourished patients and 90 malnourished patients, the relevance proportion of malnourished patients is about 63.38%. Some of the indexes were significative (P<0.05), such as ALB,WBC and so on, and the other indexes were insignificant.Conclusions:COPD patients had malnutrition of various degree when they were hospitalized. Some indexes, such as mortality rate,maintenance charge ,were significative between malnourished patients and well-nourished patients. Nutrition may play an important role in this in a large extent. So enhance the nutritional conditions would improve the prognosis and reduce the expenses of the patients family.
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