Analysis Of Risk Factors For Spontaneous Bacterial Peritonitis In Hepatic Cirrhosis

Objective: To investigate the risk factors for spontaneous bacterial peritonitis(SBP)in cirrhotic patients with ascities. Method: 200 cirrhotic patients with ascities, which were devided into two groups, the one with SBP and the other without SBP, were included in this retrospective analysis. The following factors such as sex, model for end-stage liver disease(MELD)score, child-pugh grade, liver function, clotting function, ascites routine and biochemical tests, blood routine tests, T lymphocyte subpopulations, complications, prognosis, and with or without diabetes were analyzed. Results: There were significant differences between SBP group and non-SBP group on sex, prognosis, MELD score, child-pugh grade, serum bilirubin, serum albumin, white cells in ascites, ascitic fluid albumin, neutrophil percentage,platelet count, gastrointestinal hemorrhage, hepatic encephacopathy and hepatorenal syndrome by univariate analysis.Four factors including child-pugh grade, serum bilirubin level, neutrophil percentage and ascitic fluid albumin were selected as independent factors contributing to the development of SBP by logistic regression analysis (P<0.05). Conclusion:The child-pugh grade score, serum bilirubin level, neutrophil percentage and ascitic fluid albumin were independently associated with risk factors of SBP.