Clinical Analysis Of 118 Cases With Spontaneous Bacterial Peritonitis

Object:To study the risk factors, diagnosis and treatment, related factors of prognosis of Spontaneous bacterial peritonitis. Methods: the clinical data of 118 patients with SBP in the First Affiliated Hospital of Xinjiang Medical University from May 2002 to Jan 2007 were collected, and such as predisposing factor, clinical manifestation, laboratory examination, bacterial culture, treatment and turnover were analyzed in retrospective. The statistics methods is x² test. Result: Fifty-three patients had predisposing factor in 118 patients, and gastrointestinal hemorrhage was the very common predisposing factor. Only five patients had typical manifestations of peritonitis. Abdominal distention was the very common clinical manifestation. Complacation such as hepatorenal syndrome, hepatic encephalopathy, electrolyte disturbance, gastrointestinal hemorrhage and infection of other parts and so on were found in 47 patients. 22 patients had high leukocyte count. The patients distributed into Child-pugh A, B, C were 12(10.2%), 66(55.9%), 40(33.9%). There were 9 positive results in ascitic bacterial culture. G" bacterium was about 66.7%. Patients were treated with the 3^rd cephalosporin, quinolones and albumin. 75 patients were responsive to therapy. The liver function and the complications had significant effect on the final prognosis. Conclusion: SBP is the common and serious complication for late-stage cirrhotic patient and severe hepatitis patient. It can not be easily diagnosed only by clinical manifestation for usually lacking typical manifestation. Ascites examination is the most effective and objective method for the diagnosis of SBP. All patients suspected of SBP should receive ascites examination if without counterindication of abdominal paracentesis. The patient should be treated in time when he or she was diagnosed with SBP. The liver function and the complications had significant effect on the final prognosis.