An Clinical Study On The Application Of Individualized Laser Photocoagulation In Moderate Nonproliferative Diabetic Retinopathy

Objective: To explore the effects of retinal function with individualized diabetic retinopathy laser photocoagulation which guided by the FFA (Fundus fluorescein angiography) computer image information .Methods: 60 cases (110eyes) with indications of laser therapy moderate non-proliferative diabetic retinopathy according to the different methods were randomly divided into two groups, each group 30 cases. Individualized laser photocoagulation with guided by the FFA computer image information was performed on the experimental group and pan retinal photocoagulation(PRP) by the traditional FFA image was performed on the control group,The follow-up was 24weeks.The effects of retinal light sensitivity, macular edema , visual acuity,microaneurysms ,neovascularization ,capillary nonperfusion ,postoperative complications were analyzed.Results: Retinal light sensitivity was reduced by laser photocoagulation in the experimental group and control group. It was significantly lower in the experimental group that decreased 1.23±0.47dB than in the control group (p<0.05)that decreased 2.88±0.68 dB.There was no significant difference(p>0.05) in the experimental group but significant difference (p<0.05) in control group in the preoperative and postoperative;There was no significant difference on macular edema,neovascularization ,visual acuity, capillary nonperfusion, postoperative complications between two groups (p>0.05).Conclusion: Laser surgery reduced the retinal light sensitivity. Individual methods can effectively achieve the purpose of retinal laser photocoagulation therapy and the retinal dysfunction significantly less than the control group. Application of individualized laser photocoagulation treatments had no significant increase the risk of visual loss and other complications in early diabetic retinopathy.