Qu Shi Sheng Fa Fang Treatment Androgenic Alopecia Clinical Observation And Hair Experimental Research

Objective:Using scanning electron microscopy with energy dispersion X-ray microanalysis to observe the germinal side "Qu shi sheng fa fang" treatment of androgenic alopecia before and afte-r treatment the clinical efficacy and ultrastructural changes of hair and its local chemical element content in hair.Method:111 cases of semi-randomized control patients are divided into treatment group (67 cases) and control group (44 cases), treatment for 3 months, objective evaluation of efficacy and associated symptoms improve the situation. The treatment group 67 cases, give " qu shi sheng fa fang " Treating; control group,44 cases give oral finasteride; are observed for 3 months after the hair loss and hair growth to improve the situation, and the greasy hair, itching, and dandruff number and other symptoms associated with the situation, and the analysis of 111 cases of hair loss before and after treatment in patients with hair ultrastructure and chemical element content changes, and with 50 normal people's hair for comparison.Result: The treatment group, the total effective rate is 73.1%; the control group, the total effective rate is 68.2%. The treatment group, the total efficiency are both higher than that byχ2 test, P= 0.005<0.05) the total effective rate between the two groups compared with statistical significance. Two points after the treatment condition significantly lower than those before treatment (P<0.05); the two groups before and after treatment the number of scalp scaling, greasy, hair loss, itching degree of improvement compared to the group compared the two groups were improved (P<0.05), hair loss, although the extent of the two groups after treatment no difference, but the other three clinical Chinese medicine group is significantly superior to western medicine control group. The results showed that patients ultrastructure of hair than before treatment improved chemical elements in hair before and after treatment with different degrees of change, prompted "Qu shi sheng fa fang"germinal side and finasteride chemical elements in the hair of patients have some influence, which reveals the Chinese medicine and treatment finasteride androgenic alopecia, another possible pathway.Significance:The study confirmed the "Qu shi sheng fa fang" germinal side effect of treatment of androgenic alopecia reliability, and can better improve the clinical symptoms. Combination of scanning electron microscopy energy dispersion X-ray microanalysis is intended for patients with hair hair ultrastructure and chemical element analysis, in order to further study the pathogenesis of this disease and treatment of developing new ideas.