Study On Risk Factors For Nosocomial Infection Of Acinetobacter Baummanii In Medical Intensive Care Unit

【Objective】To explore the risk factors for nosocomial infection of Acinetobacter baummanii in MICU.【Methods】A case-control study was carried out in MICU from January 2007 to march 2009 in one integrated hospital. Cases were patients with the nosocomial infection of Acinetobacter baummanii and controls were those without nosocomial infections. The match conditions were same gender, age and department. Prospective study was carried out from April 2009 to December 2009. Data was inputted by using EpiData 3.02. Conditional logistic regression was performed to identify independent risk factors in case-control study, while Cox regression model analysis was performed to identify independent risk factors in prospective study.【Results】1 1:2 case-control studyThe independent risk factors of nosocomial infection with Acinetobacter baummanii were APACHEⅡscores systembe equal or greater than 20 (OR=17.61, 95%CI=4.04-76.88),suctioning (OR=2.87,95%CI=1.26-6.51),using respiratory machine (OR=3.17,95%CI=1.45-6.95), durstion of nasal feeding tube (OR=4.25, 95%CI=1.82-9.95), maintaining vascular access devices (OR=3.07,95%CI =1.17-8.04).2 Prospective studyThe nosocomial infection case-times ineidence was 35.97% in MICU. Acinetobacter baummanii was the most commonly identified bacterial(31.25%). The independent risk factors of nosocomial infection with Acinetobacter baummanii were APACHEⅡscores system be equal or greater than 20 (RR=9.47,95%CI=1.18-76.04), using glucocorticoid (RR=2.56,95%CI=1.21-5.45), suctioning (RR=2.58, 95%CI=1.10-6.01), using respiratory machine (RR=3.53,95%CI=1.43-8.74), durstion of nasal feeding tube (RR=4.19,95%C1=1.14-15.43).【Conclusions】Acinetobacter baummanii was the most commonly bacterial of nosocomial infection. Improving MICU condition and patients' immunity reducing invasive procedures were helpful for the control and prevention of nosocomial infection of Acinetobacter baummanii in MICU.