Clinical Analysis Of Electroencephologram Minitor In Preterm Infant

Background The incidence of the preterm infant has increased in recent years, the proportion of the preterm infant in the hospitalization neonate rose quickly. With progress in medical care, the survival of preterm infants, especially those of very-low-birth-weight infants, have marked increase, and the sequelae associated with preterm birth attract more and more attention. This article investigates the relationship between the electroencephalogram (EEG) and brain injury or brain development in preterm infants.Methods 57 of the preterm infants, who were hospitalized in Division of Neonatology, the Second Xiangya hospital, Central South University between August 2009 and March 2008, were monitored the EEGs in 35-37 weeks conceptional age (CA), and used both visual and quantitative analysis of the EEG data to assess brain function and brain development.Results 57 of preterm infants were monitored EEG,,11(19.3%) had normal EEG,20 (35.1%) had mild abnormal EEG,24 (42.1%) had moderate abnormal EEG, and 2 (3.5%) had severe abnormal EEG.With the increase of gestational age and birth weight, incidence of moderate and severe abnormal EEGs significantly decreased (P<0.05) although incidence of abnormal EEGs was not affected. The incidence of moderate and severe abnormal EEGs significantly increased when Apgar score was lower than 8 score, or intracranial hemorrhage occurred.The frequency ofδbrush was significantly related to EEG abnormality. the higher frequency ofδbrush appeared, the higher abnormal degree of EEG was found (r= 0.459, P=0.001).The number of bursts per minute was less in abnormal preterm EEGs than that in normal preterm EEGs(P<0.001); Maximum burst interval (BImax) is significant longer in abnormal preterm EEGs than that in normal preterm EEGs. (P <0.001). The asymmetry was related to abnormal EEG in preterm infants. BImax was significant shorter in symmetrical preterm EEG than that in asymmetrical preterm EEG (P<0.001). The number of burst per minute was more in symmetrical preterm EEG than that in asymmetrical preterm EEG (P＜0.001). BImax was significant shorter in synchronous preterm EEG than that in a synchronous preterm EEG (P<0.001). The number of burst per minute was more in synchronous preterm EEG than that in a synchronous preterm EEG (P=0.005).Conclusions EEG monitor is important to evaluate brain function and brain development in preterm infant. The abnormal background wave is crucial in abnormal preterm EEG..