| Objective:we used MRI T2-weighted gradient echo imaging (GRE T2 * MRI) for detection of cerebral microbleeds, compared between different groups of the incidence of cerebral microbleeds, distribution characteristics of cerebral microbleeds and studied related risk factors and on the impact of cognitive dysfunction in patients.Methods:206 patients of Neurology of the Second People's Hospital of Changshu City took magnetic resonance GRE examination during2008 .12-2009. According to the existence of cerebral microbleeds, into two groups. Cerebral microbleeds positive group recorded the occurrence of cases ,the number of microbleeds, location, , record the number of lacunar infarction, leukoaraiosis situation。Record two groups of patients with blood pressure, blood lipids, blood glucose, past history of stroke .Record the score of MoCA chinese version and the MMSE scale evaluation, so as to explore the risk factors for cerebral microbleeds and with the relationship between cognitive dysfunction. All data were analyzed using SPSSl6.0.Results:Cerebral microbleeds occurred significantly associated with hypertension (P <0.01), history of stroke-related (P <0.05), and high blood lipids, and diabetes are not related (P> 0.05). The severity of cerebral microbleeds related to the severity of leucoaralosis (P <0.01). Cerebral microbleeds in predilection sites of lesions in the hemorrhagic group and the site-related. The score of MoCA in CMBs group was significantly lower than the control group witch was statistically significant (P <0.01).Conclusion:The cerebral microbleeds in patients that had history stroke have a higher incidence . CMBs are associated with hypertension, lacunar infarction, leukoaraiosis closely related. CMBs significantly associated with cognitive decline. Cerebral micro-hemorrhage is conducive to tell whether patients with small-vessel lesions and pathological changes, preventing the development of vascular dementia and improve prognosis.
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