The Time-motion Curves Of Omnidirectional M-mode Echocardiography For Assessing Left Ventricular Function In Type 2 Diabetes Mellitus Patients

Objective: The time-motion curves of the new omnidirectional M-mode echocardiography(OME)was used to provide accurate quantitative measures of the LV function in type 2 diabetes mellitus(T2DM) patients.Methods: LV functions were analyzed with conventional echocardiography and LEJ-2 OME in 30 patients with T2DM and in 30 normal subjects. Besides the routine parameters (FS, IVRT, EF, the ratio of E/A, etc.), the time to peak myocardial systolic velocities (Ts) and early-diastolic velocities(Td) that were obtained from the time-motion curves of 12 segments of the LV short-axis by OME, the standard deviation and maximum difference of Tm(Tm-12 SD,Tm-12-dif) were used to determine the LV function.Results: The differences between the patients with T2DM and the normal groups on the LV and EF were not significant(P >0.05), but LA, IVS, EDV, FS, Vp, A and the E/A ratio were differed significant (P <0.05). Ts of 12 segments of the LV short-axis and Tm-12-SD were longer in patients than in normals(P <0.05). Likewise, Td was also significantly higher in DM group except for lateral, posterior and anterior septum(P <0.05). There was not significantly difference on Tm-12-dif in the two groups(P >0.05).Conclusions: OME can provide accurate quantitative measures of LV functionin in T2DM patients and can be important additional modalities in the assessment of the region LV function. Morever,it can provide the evidence to show left ventricular asynchrony in the patients with DM. It can be considered for serial measurements.