| ObjectiveTo investigate the clinical value of speckle tracking imaging in the diagnosis of myocardial ischemia with normal ventricular wall motion.MethodsAccording to the results of coronary angiography or CT, 40 patients with coronary heart disease(CHD)and 40 age-matched subjects were erolled.The two dimensional loop-cinec were obtained in apical 4-chamber view,apical 2-chamber view and long asix of left ventricle view. The parameters, including early strain rate(SrE)and late stain rate(SrA)of diastolic phase and average globe longitudinal strain ( GLS_Avg ) , were measured and calculated. Incidence of SrE/SrA<1 and GLPS_Avg were applied to evaluate the diagnostic efficiency for CHD by receiver operating curve.ResultsDiastolic strain rate : The incidence of(SrE/SrA<1)in CHD group was significantly higher than that in control group(p<0.01).The cutoff values of incidence of SrE/SrA<1 to diagnose CHD and multi-coronary heart disease were 23.6%and 30.5% respectively,with the sensitivity 47.5% and 56.0%as well as specificity 72.5%and 80.0%. the cutoff value of incidence of SrE/SrA<1 to diagnose CHD with at least one coronary artery stenosis≥50% was26.4% ,with the sensitivity 56.7% and specificity 78.0%.Averge globe longtitude strain: GLPS_Avg in CHD was significantly decreased. The cutoff values of GLPS_Avg to diagonos CHD and CHD with at least one coronary artery stenosis≥50% were -20.7% and -19.7% respectively, with the sensitivity 87.5%and 73.3% as well as specificity 60.0%and 76.0%.The combination of two methods: Either of the standards ( the incidence of(SrE/SrA<1)≥26.4% or GLPS_Avg≤-19.7%) was met , the sensitivity and the specificity to diagnose CHD was 76.7% and 68.0% respectively. And the two standards were met simultaneously, with sensitivity of 46.7%and specificity of 84.0%.ConclusionsIncreased incidence of SrE/SrA<1 or decreased GLPS-Avg with STI technique was helpful to diagnose CHD. The accuracy to diagnosis of CHD will increase if the two methods were combined . |
