| Objective:Two-dimensional Speckle-Tracking Imaging(2D-STI)was used to evaluate the local and global left ventricular systolic function before and after coronary artery bypass grafting in patients with coronary artery disease≥3 branches.Methods:Collection of cardiothoracic surgery from our hospital from January 2017 to December 2018.Coronary artery lesions confirmed by coronary angiography≥3,and 30 patients with coronary artery disease undergoing coronary artery bypass grafting(CABG)were treated as a case group.Transthoracic echocardiography and 2D-STI were performed before surgery and 6 months after surgery.In a calm state,transthoracic echocardiography was performed,and left ventricular end-diastolic dimension(LVEDd),left ventricular ejection fraction(LVEF),and fractional shortening(FS)were routinely measured.Clear two-dimensional gray-scale dynamic images were acquired from long axis view of cardiac apex,apical four-chamber view and apical two-section view respectively,and the acquired dynamic images needed to last 3 cardiac cycles;Two-dimensional speckle tracking technique was used to measure peak longitudinal strain(PLS),globle peak longitudinal strain(GPLS)and post-systolic strain index(PSI)of each segment of left ventricular systolic phase.Thirty healthy subjects matched in sex and age were selected as control group.Results: 1.There was no significant difference in general data between the case group and the control group(P>0.05).2.Compared with the control group,LVEF,LVEDd and FS in the case group decreased before CABG(P<0.05),and the results of LVEF,LVEDd and FS improved 6 months after CABG(P<0.05).3.Compared with the control group,the peak longitudinal strain(PLS)of left ventricular ischemic myocardium segment in the case group was significantly reduced before CABG,and the difference was statistically significant(P < 0.05).The peak longitudinal strain(PLS)of left ventricular ischemic myocardium segment was increased 6 months after CABG(P<0.05).4.Compared with the control group,the global longitudinal strain peak(GPLS)in the case group decreased before operation(P<0.05),and the left ventricular GPLS increased 6 months after CABG operation(P<0.05).GPLS has good correlation with LVEF and LVEDd,with correlation coefficients of 0.81 and-0.78 respectively(P<0.05).5.Compared with the control group,the number of segments of left ventricular wall PSI>0 in the case group increased significantly before operation(P<0.05),and the number of segments of left ventricular wall PSI>0 decreased 6 months after CABG(P<0.05).Conclusion: 1.PLS and PSI can accurately evaluate the local and global myocardial systolic function of left ventricular wall in patients with coronary heart disease with ≥ 3 branches of diseased coronary artery.2.PLS and PSI can accurately evaluate the recovery of regional and global left ventricular systolic function in patients with coronary heart disease with ≥3 branches of diseased coronary artery after CABG,thus reflecting the clinical therapeutic effect. |
