Study On The Left Ventricular Mechanical Changes In Patients With Coronary Heart Disease By Speckle Tracking Imaging

ObjectiveTo evaluate the left ventricular mechanical changes in patients with coronary heart disease (CHD) through the detection to systolic strain changes of myocardial ischemia segments by using two-dimensional speckle tracking imaging (2D-STI).MethodsThere were 60 cases of CHD patients and 30 cases of normal controls were collected on this study. We collected their apical two-chamber-bit section, four-chamber section, left ventricular long-axis and left ventricular short-axis (mitral valve level, papillary muscle level, apical level) of 18 segments of high frame rate two-dimensional gray-scale images. Measured the different segmental systolic longitudinal strain (LS), strain peak time, systolic radial strain (RS), strain peak time, systolic circumferential strain (CS), strain peak time, and left ventricular short-axis basal and apical rotation angle peak, peak time by two-dimensional strain software respectively, and calculated the left ventricular overall torsion angle peak, peak time.Results1,There were 221 ischemia segments in CHD patients, 202 segments of which were successfully obtained by two-dimensional speckle tracking technology.2,The Left ventricular end diastolic diameter(LVEDD), Left systolic end diastolic diameter(LVESD) of CHD patients were more than that of the controls, this difference had statistically significant(P<0.01) ; the E jection frac tion,E value of Mitral valve and E/A of CHD cases were less than that of the controls ,these difference had statistically significant(P<0.05). the A value of Mitral valve and E/A of CHD cases were more than that of the controls ,these difference had statistically significant(P<0.05).3,The maximum of systolic longitudinal,radial and circumferential strain peak value of left ventricular short-axis (mitral valve level, papillary muscle level, apical level) in patients with CHD were all lower than those of the controls, and their peak time were longer than those of controls. All these difference had statistically significant (P<0.01).4,The left ventricular short-axis basal and apical rotation angle peak and the left ventricular overall torsion angle peak of CHD cases were all lower than those of controls, and the peak time was longer than that of controls. All these difference had statistically significant (P<0.01).5,Overall left ventricular torsion angle and LVEDV (r=-0.53, P<0.01), LVESV (r=-0.54, P<0.01) were correlation; Overall left ventricular torsion angle and LVEF (r=0.64, P<0.01) were significant correlation.Conclusions1,There were left ventricular local myocardial motion abnormalities in CHD patients and their left ventricular systolic function was lower than that of the control cases.2,The method of strain index combined with traditional echocardiography can successfully evaluate the mechanical changes of CHD patients.3,STI may accurately evaluate the strain index of different segments of left ventricle which provide a new method for evaluating left ventricular systolic function in patients with CHD.