Analysis Of Related Factors And Outcomes Of Gestational Diabetes Mellitus Between Different Nationalities In Xinjiang

Objective: To study the risk factors of Gestational Diabetes mellitus(Gestational Diabetes mellitus GDM) and its effect on the Pregnancy outcome.between minorities (Kazakh and Uygur) and Hans pregnant wemen in Xinjiang. Methods: The clinical data in 195 patients with GDM and 132 patients with normal Blood glucose were analyzed retrospectively. The 195 pregnant wemen with GDM composing the case group were divided into two groups according to different ethnicities. Minorities group(n=58) and Hans group(n=137). With the same method, the 132 pregnant wemen with normal blood glucose composing the control group were divided into minorities group(n=62) and Hans group(n=70). To analyse the effect of related factors on the case group and the control group. To analyse about the outcomes of mothers and their neonates,to compare the outcomes of mothers and their neonates between GDM group and normal glucose group,to study the effect of GDM on mothers and their neonates. Results:1.Using the logistic analyse the major suspect risk factors of GDM were weigh before delivery and family diabetic history of mother in minorities,while the high risk factors of the Hans group were weigh before pregnancy and age.2.To compare the complications and outcomes of mother in the case group to the control group of different ethnicities using chi-square test. The result showed that the incidence rate of complications and outcomes including intrahepatic cholestasis of pregnancy (ICP),preeclampsia,prematurely delivery and premature rupture of membranes(PROM) in Hans' case group was higher than the one of the control group.The result had a statistical significance(respective P<0.05).Among Kazakhs and Uygurs,the incidence rate of ICP born infant and preeclampsia was higher,while the incidence rate of anemia was lower,the result of which had a statistical significance(respective P<0.05).3.The outcomes of perinatal infants were compared also using chi-square test.Significant differences exist(respective P<0.05) between the case group and the control group of Hans including fetal distress, fetal macrosomia, neonatal hypoglycemia and intracranial hemorrhage of the newborn.Among the minorities, the incident rate of asphyxia neonatorum,fetal macrosomia and neonatal hypoglycemia was significant difference(P<0.05). Conclusion:1. The major risk factors were weigh before delivery and family diabetic history of mother in minorities and weigh before pregnancy and age of in Hans.2.GDM had conspicuous influence on the patients with a diagnosis of GDM. It could rise the incidence rate of ICP, preeclampsia,prematurely delivery and PROM in Hans and the former two ones are the same as Kazakhs and Uygurs, whose anemia incidence declined.3.GDM had obvious influence on the perinatal infants: It could increase the incidence rate of fetal distress, prematurely born infant,fetal macrosomia, neonatal hypoglycemia and intracranial hemorrhage of the newborn and asphyxia neonatorum, in Kazakhs,Uygurs and Hans.