| Objective:By analyzing the clinical data of hypertensive intracerebral hemorrhage (HICH) cases in Chenzhou from January 2007 to January 2010 to generalize the characteristics of HICH.Methods:1.The cases of HICH (n=599)diagnosed by CT or MRI were selected from January 2007 to January 2010 in Chenzhou .which were classified into four age group as following: younger group(<45yrs),middle-aged group (45~59yrs), older group (60~74 yrs) and the oldest group(≥75yrs). Analyzed the differences of etiological factors, features, clinical symptom, objective sign, laboratory examination and image data among the four age groups.2. SPSS 17.0 software was adopted to analyze data and make graphs. Calculated data presented with ( X±S). Numerical data were presented by frequency and percentage.t test was applied to compare the difference between two calculated data, and Pearson chi-square test was applied to compare the differences of numerical and 0.05 was statistic value.Results:1. 599 cases with male (n=407, 67.9%) and female(n=192, 32.1%) were selected, the ratio of sex was 2.12:1, Ages of which spaned from 26 to 87 yrs (58.58±11.97 yrs). Four age groups as following: younger group (n=71, 11.9%), middle-aged group (n=246, 41.4%), older group (n=224, 37.4%), the oldest group (n=58, 9.7%).2. Compared the difference of onset among spring (n=117, 19.53%), summer (n=102, 17.03%), autumn (n=167, 22.88%) and winter (n=213, 36.5%), there was a significant difference among them.3. Compared the difference of onset among four periods of day as following: 0.00 to 5:59 (n=86, 14.36%), 6.00 to 11:59 (n=233, 38.90%), 12.00 to17:59 (n=143, 23.87%) and 18.00 to 23:59 (n=137, 22.97%), there was a significant difference among which.4. 147 cases used to smoke (male: n=138, female: n=10),and 143 cases with alcohol abuse (male: n=133, female: n=10), there was a significant difference between male and female of which respectively. 396 cases have familial history of hypertensive disease (male: n=268, female: n=128), 74 cases have familial history of cerebral apoplexy (male: n=48, female: n=26), and 45 cases have history of diabetes (male: n=30, female: n= 15), there was no significant difference between male and female of which respectively.5. Onset of HICH in the condition of resting state were 81 cases (13.5%), while 518 cases (86.5%) began in the condition of movement.6. Compared the difference of average diastolic blood pressure among four age groups as following: younger group (96.49±4.42 mmHg), middle-aged group (104.76±19.60mmHg), odler group (99.41±17.91mmHg), the odlest group(96.62±19.64mmHg), there was a signifacant difference among which.Meanwhile compared the difference of average systolic blood pressure among four age groups as following: younger group (166.58±27.06mmHg), middle-aged group(174.48±28.90mmHg), odler group (175.67±25.74mmHg), the odlest group (175.67±25.74mmHg), there was no signifacant difference among which.7. 211 cases (35.2%) with abnormal conscious,255 cases (42.6%) with head -ache, 89 cases (14.9%) with dizziness, 264 cases (44.1%) with vomiting, 206 cases (34.4%) with incontinence, 44 cases (7.3%) with seizure, 63 cases (10.6%) with phasia, 211 cases (35.5%) with meningeal irritation, 139 case (23.3%) with visual impairment, 164 cases (27.4%) with eye movement disorder, 165 cases (27.5%) with pupil abnormalities, 335 cases (55.9%) with facial paralysis, 312 cases (52.1%) with tongue paralysis, 68 cases (11.4%) with dysphagia, 94 cases (15.7%) with ataxia, 401 cases ( 66.9%) with limb paralysis, 248 (41.4%) with abnormal sensory, 63 cases (10.6%) with mental symtoms, 236 cases (39.4%) with abnormal muscle tone (increased:214 cases, reduced:203 cases), 364 cases (59.1%) with positive patholo -gical sign.8. Descending order of bleeding parts :basal ganglia (n=355, 59.3%),lobe of brain(n=70, 11.7%), brain stem (n=63, 10.5%), cerebellum(n=66, 11.0%) , ventricle (n=32, 5.3%), the remaining parts(n=13, 2.2%).9. Average blooding volume of was 22.56±14.11ml (0.50~82.00ml).Compared the difference of which among different blooding parts as following: lobar (32.47±17.00ml, 4.00~82.00ml), basal ganglia (25.98±11.80 ml, 5.00~70.80ml), cerebellum (14.92±6.31ml, 2.00~30.80ml), other parts (5.85±1.46ml, 3.60~8.00ml), brainstem (3.80±1.68ml, 0.50~10.80ml), and there was a significant difference between any two blooding parts10. The mean TG, TC, LDL-C and HDL-C were 1.56±1.50mmol/l, 4.75±1.05 mmol/l , 2.65±0.83 mmol/l and 0.96±0.40 mmol/l respectively, lower than the risk critical level of which (TG 2.26mmol/l,TC 6.22mmol/l,LDL-C 4.14 mmol/l,HDL-C 1.04 mmol/l) respectively. Compared the mean HDL-C among different age groups, there was a significant difference between any two age groups (younger group: 1.41±0.50 mmol/l, middle-aged group: 1.00±0.37 mmol/l, odler group: 0.87±0.35 mmol/l, the odlest group: 0.66±0.17 mmol/l).Compared the TC betweem male and female of different age groups,the difference was significant in middle-aged group(male: 4.65±0.95mmol/l, female: 5.03±1.09mmol/l), odler group (male: 4.61±1.02mmol/l, fem- ale: 5.19±0.84 mmol/l), and the odlest group (male: 3.87±1.29 mmol/l ,female: l.53±0.97 mmol/l).Conclusion1.The increase in diastolic blood pressure can be one of the important factors for HICH in Chenzhou.2. TG, TC, LDL-C and HDL-C level lower than dangerous level respectively can be another factor of HICH in Chenzhou.
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