The Analysis Of Infection Of Brain Injury Of Little Gestational Preterm Infants With Maternal Chorioamnionitis

Objective: To explore the maternal chorioamnionitis how to infect brain injury (include periventricular leukomalacia (PVL) and periventricular intraventricular hemorrhage(PVH-IVH)) of the preterm infants. Methods: 88 preterm infants (include 28weeks-34weeks)were selected from our hospital from June 2008 to October 2010. The cases were divided into two groups according to the results of maternal chorioamnionitis. Infants with maternal chorioamnionitis was 41 cases. And the control group was infants without maternal chorioamnionitis, include 47 cases. All the infants were checked by head ultrasonography from 3~7days after born and repeatly were checked every one week during newborn period. Then all the infants were checked every two or four weeks until three months after born, about six to eight times in all. All the infants were checked by head magnetic resonance imaging (MRI) after correcting age 40 weeks. To observe the occurrence of the periventricular leukomalacia and periventricular intraventricular hemorrhage of preterm infants in two groups. Results: The incidence of periventricular leukomalacia (PVL) in the group with maternal chorioamnionitis was 31.7%, which was significantly higher than the group without maternal chorioamnionitis group's (6.4%).(P<0·05).But the incidence of periventricular intraventricular hemorrhage(PVH-IVH) in the group with maternal chorioamnionitis was 26.8%, while without maternal chorioamnionitis group's was 23.4%.There were no obvious diffierence in two groups.(P > 0·05). Conclusion: The maternal Chorioamnionitis is associate with the brain injury of preterm infants. It can make the incidence of PVL of the preterm infants increase. But it has not infect the incidence of PVH-IVH obviously.