Study Of Charged Particle Therapy Planning System Based On CT Technology

This work introduces four parts: the history of the charged particle treatment, the problems of the charged particle treatment planning system,the main features of CT technology and the application of CT simulation in radiotherapy. Then the CT technology and the energy loss of charged particles with matter and the range of other substances wereincluded, following the theoretical and experimental methods and results. Conclusions are given finally.The protocol of this work is study the proportional coefficient of range (CZEi) of Charged particles beam (protons: 70MeV-250MeV, carbon ions: single nuclear energy 80MeV～500MeV, neon ions: single-core energy of 100MeV-700MeV) in a variety of radiation equivalent material and the range of Charged particles beam in water at the same energy region. By analyzing the characteristics of electronic energy loss and nuclear energy loss, and using Monte Carlo program of SRIM2008, we calculated the range of charged particles (protons:0.01MeV～250 MeV, carbon ions: single nuclear energy O.OlMeV～500MeV, neon ions:single-core energy of O.OlMeV-700MeV) in water, air, bone tissue equivalent material and muscle tissue equivalent material.We found that this proportional coefficient of range (CZEi) values is a constant in the treatment of the energy range of protons, carbon ions and neon ions, in the air,bone equivalent material, muscle equivalent materials, which mainly determined by the characteristics of radiation tissue equivalent material. The size of charged particles in the current incident energy region is relatively small.Selecting a different incident energy of charged particles (protons: 150MeV and 250MeV, carbon ions: single-core energy 350MeV and 450MeV, neon ions: single-core energy 400MeV and 600MeV),we used Monte Carlo method SRIM2008 procedures to verify this proportional coefficient of range (CZEi). Particular incident radiation energy charged particles in tissue equivalent materials, the actual range can be translated into the water equivalent range, according to the various materials and water proportional coefficient of range (CZEi). The differences of the ranges of different energy charged particles in the water and the average water equivalent range of the actual are within 1%. The differences dectease with the energy incteaseing of incident particles, with the incident particle atomic number inceasing.