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Chronic Obstructive Pulmonary Disease Stabilization Traditional Chinese Medicine Combined Efficacy Evaluation Model Of The Preliminary Discussion

Posted on:2012-01-01Degree:MasterType:Thesis
Country:ChinaCandidate:Y X LiuFull Text:PDF
GTID:2154330335968132Subject:Traditional Chinese Medicine
Abstract/Summary:PDF Full Text Request
BackgroundClinical therapeutic effect of TCM's life, The theory was established on the basis of rigorous, scientific evaluation method of clinical curative effect of Chinese medicine, for that research is the most important. Traditional Chinese medicine is a systematic theoretical system and unique diagnostic methods,its concerns about living quality and characteristics of indiidual therapy with the development trend of modern medicine alike. But the heoretical system of the western and Chinese medicine clinical treatment, As a result of between of these two theories exist great different. Chinese medicine clinical clinical treatment is mainly dialectic as first. The corresponding relation of the unknown effect assessment of traditional Chinese medicine content, methods of measurement exist some problems, and mechanism of traditional Chinese medicine also unclear, Although TCM in clinical curative effect is distinct.But it's hard to set up a more standard and scientific TCM theory system, so the more difficult to walk to walk into relative scientific research world. How to definite effect of traditional Chinese medicine common disease frequently—occurring disease difficult and rare case to use, And use of scientific methods and tools to rationally explain the curative effect of TCM. And how to use that international language interpretation the curative effect of traditional Chinese medicine cure and let the world recognized in traditional Chinese medicine, This is in chinese medicine can the keypoint international mainstream medicine.ObjectivesThis study was to use the principle of evidence-based medicine and methods, analysis of the clinical curative effect of Chinese medicine stabilization of COPD evaluation and structural method. It is beneficial in comprehensive, truly, objectively evaluate the stabilization of COPD stable stage for TCM clinical effect. And we hope use "international general medical language" clarify Chinese medicine, especially the compound of the clinical curative effect of traditional Chinese medicine, the popularization, toward the world will have far-reaching effects.MethodsA multi-center randomized double-blind controlled clinical trials method. This is match can be integrated into the standard chronic obstructive pulmonary disease(COPD)stabilization patients, and randomly divided into two groups, TCM treatnent group and placebo group, both groups give western medicine foundation to treatment, two month period, follow-up 4 months. In treatment, before and after, ending at the end of the follow-up evaluation index, pathology, mainly impairment levels, administrative levels, disability level, the overall state evaluation, and carry on comprehensive evaluation, safety evaluation, syndromes efficacy so different levels of evaluation, observation of TCM therapy for COPD stabilization of long-term clinical curative effect and the influence of prognosis, and through statistical analysis like using the factor analysis, principal component analysis method to analyze the composition of each index and its relation, Than we discusses the evaluation of clinical curative effect of traditional Chinese medicine stabilization of COPD the basic content and structure.ResultResults showed that TCM treatment can reduce patients with COPD acute exacerbation time is reduced, after treatment, increase total SGRQ six minutes walking distance through the improvement of symptoms, and raising the syndromes curative effect, and adverse reaction rate'low, good safety. Secondly, according to the different observing indexes of evaluation index of comprehensive statistics effect analysis, the initial formation of COPD patients with stable TCM comprehensive therapeutic indexes system contains the following six hierarchy indicators:main end index (acute exacerbation times), pathological levels (lung function and nutrition) and disabled levels (survival quality SGRQ rating), functional impairment levels (6 minutes walking distance), comprehensive index (BODE index), and body overall state evaluation (syndromes curative effect). Each hierarchy indicators respective included several observation index, nutrition index five, pulmonary function index 4, TCM symptoms of three, the main outcome curative effect and comprehensive index, index athletic stamina index, disabled hierarchy indicators 1. After inspection has certain structural validity and content validity and reliability, initially formed contains 16 index, TCM comprehensive effect the stationary COPD appraisal system, and illustrates the composition and classification.ConclusionPreliminary form COPD patients with stable TCM comprehensive therapeutic indexes system contains the following six hierarchy indicators:main end index (acute exacerbation times), pathological levels (lung function and nutrition) and disabled levels (survival quality SGRQ rating), functional impairment levels (6 minutes walking distance), comprehensive index (BODE index), and body overall state evaluation (syndromes curative effect). Each hierarchy indicators respective included several observation index, nutrition index five, pulmonary function index 4, TCM symptoms of three, the main outcome curative effect and comprehensive index, index athletic stamina index, disabled hierarchy indicators 1. After inspection has certain structural validity and content validity and reliability. Among them with nutrition index, pulmonary function indexes in the whole process of research both observe as chronic obstructive pulmonary disease stabilization effect assessment system of TCM intervention main index. TCM symptoms therapeutic indexes, sports endurance index, Tradition chinese medicine in COPD stabilization effect assessment system is stable observation above index for its main index ending.
Keywords/Search Tags:Chronic obstructive pulmonary disease, TCM therapy, Effect assessment mode, factor analysis
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