Clinical Correlation Analysis Of Nutritional Status In Patients With Chronic Obstructive Pulmonary Disease

Objective: The purpose of this study is to evaluate the nutritional status of hospitalized COPD patients through a simple and effective evaluation method,to investigate the nutritional status of COPD patients during hospitalization,and to explore the effects of malnutrition on the body and quality of life of COPD patients,so as to provide a basis for nutritional intervention of COPD patients so that clinicians can manage them more effectively.Methods: a total of 80 patients with COPD who were hospitalized in the first ward of the respiratory department of our hospital from December2019 to November 2020 were collected.Within 24 hours after admission,the patients were assessed by mini-nutritional assessment method(MNA-SF),and the patients were divided into groups according to the results of the assessment.MNA-SF ≥ 11 was divided into normal nutrition group,MNA-SF < 11 as malnutrition group.The general data,body mass index(BMI),chronic obstructive pulmonary disease assessment test(CAT score),C-reactive protein(CRP),pulmonary function(FEV1%,FEV1/FVC%,PEF%,MVV%),arterial blood gas analysis(p H,PO2,PCO2),biochemical indexes(ALB,PAB,HB,TG,TC,LC)and hospitalization days were compared between the two groups of patients with different nutritional status.And to explore the correlation between MNA-SF value and CAT score,CRP,pulmonary function and arterial blood gas analysis.Results: among the 80 hospitalized COPD patients,there were 45(56.25%)in the normal nutrition group and 35(43.75%)in the malnutrition group.There was no significant difference in sex and age between the two groups of COPD patients.The BMI,ALB,PAB,PO2,FEV1%,FEV1/FVC%,PEF% and MVV% in the malnutrition group were lower than those in the normal nutrition group,while the constituent ratio of CRP,PCO2,respiratory failure and CAT score in the malnutrition group were higher than those in the normal nutrition group(p < 0.05).There was no significant difference in p H,some biochemical indexes(HB,TG,TC,LC)and hospitalization days between the two groups.MNA-SF was negatively correlated with CAT score,CRP and PCO2(r=-0.266、-0.226、-0.486,p<0.05),and positively correlated with FEV1%,FEV1/FVC%,MVV%,PEF% and PO2(r=0.379、0.334、0.286、0.284、0.313,p<0.05).Conclusion: 1.Hospitalized patients with COPD generally have varying degrees of nutritional problems,and the incidence of malnutrition in this study reached 43.75%.2.The cases of underweight,hypoproteinemia and respiratory failure in COPD patients with malnutrition were significantly higher than those in patients with normal nutrition.3.The nutritional status of patients is closely related to CRP,CAT score,pulmonary function and blood gas analysis.Improving the nutritional status of patients may be helpful to the improvement of pulmonary function,quality of life and disease prognosis.