Clinical Analysis Of The Gallstones With Gallbladder Cancer

Objective:To investigate the relationship between gallstones and gallbladder cancer.Method:My department in January 2005 to January 2011, the combined gallbladder gallstone admitted 17 patients (A group) and the same period, surgical resection of gallbladder stones in 30 patients (B group) were retrospectively analysis.Result:A group of female patients accounted for 64.71% of patients (11/17), age over 55 accounted for 76.47%(13/17); a history of chronic cholecystitis time, A group of 11 patients with a history of time in patients 15 years the highest proportion (47.06%), B time in the history of patients 6 to 10 years, the highest proportion of patients (53.33%);Clinical symptoms, A group of patients 64.7% (11/17) associated with persistent upper abdominal pain, skin stained yellow sclera, significant weight loss and other symptoms of advanced gallbladder carcinoma, and 73.33% patients in group B with intermittent upper abdominal pain, nausea, vomiting based; 1 year before admission, episodes of abdominal pain, A group of patients with onset≥3 times the highest proportion (47.06%), B group 1 patients with the highest proportion of seizures (47.06%). By imaging studies, A, B groups in the preoperative diagnosis rate was 70.59%(12/17) and 100%(30/30).Gallstone diameter, A group of gallstone≥2cm in diameter accounted for 64.71%, B≥2cm in diameter gallstone group accounted for 26.67%.A group of patients with pathological stage,Ⅰof accounting for 11.76%(2/17),Ⅱof accounting for 23.53%(4/17),Ⅲof accounting for 41.18%(7/17), IV of 23.53%(4/17.) Surgical, A group of patients received radical resection and only 29.42%(5/17), B group of patients through the surgical cure rate was 100%.Conclusion:1. Gallstones may be one of the important factors inducing gallbladder.2. gallstone patients suffering from gallbladder cancer risk factors:①women,②above the age of 55 years,③history of chronic cholecystitis in 10 years,④repeated episodes of abdominal pain in 1 year,⑤imaging studies suggest gallbladder contraction, gallbladder wall thickening or abnormal shape of the gallbladder,⑥gallstone diameter≥2cm,⑦"porcelain gallbladder'3. possible for a gallstone cancer patients should take active preventive cholecystectomy.