Clinical Prognosis With The Different Treatment Modalities For Primary Liver Cancer(PLC) Alleviative Treatment

Objective:to evaluate survival rate condition of current four frequent treatment modalities for primar liver cancer,in order to discuss advancedly the best selection about therapy method for liver cancer.Methods:a retrospective analysis of 188 patients of PLC received four frequent treatment our hospital,among them,33 cases which were included in intervention group were treated with alleviative treatment,67 cases were in transcatheter hepatic chemoembolization(TACE);65 cases were in TACE+surgery,to go on intervention treatment after surgery,or in some cases with larger tumor,to go on intervention treatment before surgery,waiting tumor stage is downgraded,or tumor is contracted.To go on resection of liver lobe or segments of liver,intervention way is still transcatheter hepatic chemo-embolization;23 cases included TACE+Radiotherapy, after TACE,go on 3-dimensional conformal radiotherapy for hepatocellular local tumor.The test of rate uses Row-Column tables x2 test,survival rates were assessed from the date of the beginning of treatment using the Kaplan-Meier method.The survival rates of three groups were compared using Log-rank.Results:1 year,2 years,3 years survival rate:alleviative treatment:69.7%,51.5%,36.4%, TACE group:71.6%.44.8%,22.4%,TACE+S:92.3%,72.3%,52.3%, TACE+RT:82.6%,60.9%, 43.5%.The Row-Column table x2 tests of overall survival rates for four frequent treatment modalities were all significantly different(P<0.05).The 4th-Cell table x2 test of the 2-2 analysis among survival rates for four frequent treatment modalities were significantly different only between two and three group(P<0.05/4=0.0125).The survival analysis of four therapic groups using the Kaplan-Meier method was significantly different among four group.Means for Survival Time among the four terapy groups were 26,24,44and32 monthes respectively The Log-Rank test of the 2-2 analysis among three groups were significantly different only between two and three group.Conclusions:the survival rate of the TACE therapy combined with S or RT was significantly higher than the single TACE between the comprehensive treatments of PLC on the base of the TACE therapy.The survival rates of the TACE+S were greatly highest among four groups.According to survival plot,among the survival rates of four group,TACE+S>TACE+RT>alleviative treatment>TACE group.