A Clinical Study Of Bi Syndrome With Different Differentiation By Apitherapy

BackgroundApitherapy is a unique therapies which takes the bee sting as a needle and prods into acupoints on the basis of the principle of acupuncture for disease prevention and control. It is significant to cure some disease especially rheumatoid arthritis and Ankylosing Spondylitis etc. which are still dependent on Corticosteroids. Syndrome differentiation and treatment has instruction function in the TCM. This article was based on the Apitherapy to treat different type of Arthralgia Syndrome associated with the clinical efficacy analysis, to investigate whether the curative effect of Apitherapy was related to TCM syndrome type.ObjectiveThis research to investigate the curative effect of different syndrome types of Arthralgia Syndrome and to make sure the difference of the therapeutic efficacy of them, so it provides theoretical foundation for apitherapy to treat Arthralgia Syndrome, and promotes extensive use in the clinical.MethodsAccording to syndrome differentiation and divided 65 cases who measured up to standard into 4 groups which contain anemofrigid-damp arthralgia group,wind heat and moisture group,Phlegm Stasis-Bizu group,kidney and liver insufficiency group. Patients in each group used live bee sting, and maked sure prod into acupoint. The first time only used one bee needle, and extract immediately (not squeeze Poison sac.). The first ten times were used within 2 bee needles, and increased 1 bee needle by degrees depend on the patient's condition. Each increment was subject to the Previous response or no discomfort mild swelling response but could not tolerated Prevail. The time of needle retaining was asked for 20 minutes. If a high fever (T> 39℃),serious pruritus and swell during the Period,we may reduce the number of bee needle.Used at least one bee needle and 25 bee needles at most one time. General 3-10 bee needles/twice a week were asked for. At least 2 time Treatments one week, 10 times as a course of treatment,2 courses in all. Points general choosed BL 23,ST36,SJ5 etc. which in the hand-foot-lateral position and the waist Points. Used statistical software SPSS13.0 to analyse data.Results1. Comparison of general condition,symptoms and signs before treatment:(1) Anemofrigid-damp arthralgia group included 7 males and 11 females, and mean age was 49.89±15.87; wind heat and moisture group included 6 males and 10 females, and mean age was 42.94±15.58; phlegm stasis-bizu group included 5 males and 8 females, and the average age 49.62±20.95; kidney and liver insufficiency group consisted of 5 males and 13 females, and mean age 49.62±20.9. These patients mostly were women and concentrated in the age of 25-35 years and 50-65 years old, and the highest ratio was in the liver and kidney virtual group. Four groups with age, sex by statistical test, respectively P=0.418 and P=0.888, the difference was not statistically significant (P> 0.05), four groups were comparable.(2) The average course of disease of four groups were 11.41±11.44 years, 5.30±5.07 years,12.81±12.89 and 6.00±5.99 years; Along the disease development with an increased incidence of anemofrigid-damp arthralgia group and kidney and liver insufficiency group; The long-term course of each node card to the more common in phlegm stasis-bizu group, but wind heat and moisture group was short-term course. Four groups were tested by statistics course, the difference was not statistically significant (P=0.062>0.05), suggested four groups can comparable.(3) The difference of the number of joint Pain, VAS, TJC, joint swelling and joint movement disorder were not statistically significant.2. The comparison of four groups of patients with symptoms, signs, effective after treatment:(1) The difference of VAS and TJC were marked improvement after the treatment (P<0.05), and there was not different between groups. Number of joint Pain: anemofrigid-damp arthralgia group,phlegm stasis-bizu group and kidney and liver insufficiency group were marked improvement after the treatment (P<0.05), but wind heat and moisture group was no significant improvement. Joint swelling:wind heat and moisture group was improved significantly (P<0.05), and the other three groups were not significantly improve the joint swelling (P>0.05). Joint movement disorder:wind heat and moisture group and Phlegm Stasis-Bizu group improved significantly (P<0.05), but the improvement that anemofrigid-damp arthralgia group and kidney and liver insufficiency group were no obvious.(2) The short-term control was 9.2% after treatment in all Patients, excellent was 15.4%, effective was 66.2%, total effective was 90.8%. Among them, the total effective rate was 82.9% of rheumatoid arthritis. Comparison of effects among different cavity diseases, P=0.212>0.05, suggested efficacy was similar in above-mentioned disease.(3) The Comparison of total effective between different syndromes, P= 0.942>0.05, suggested that there was similar efficacy between different syndromes.Conclusions1. Apitherapy is a definite effective way in treatment of Arthralgia Syndrome, and the total effective rate was 90.8%. There is not different between different syndromes suggested that Apitherapy is a general effect treatment for different syndromes of Arthralgia Syndrome2. Apitherapy has a significant effect in VAS and TJC, and there is not different between different syndromes3. wind heat and moisture group and Phlegm Stasis-Bizu group are better than other groups in the side of TJC,joint swelling and joint movement disorder4. Apitherapy is not obvious related to different syndromes of Ankylosing Spondylitis.