The Clinical Observation Of Analgesic Action On Apitherapy To Primary Liver Cancer Patients

ObjectiveThis study used apitherapy and analgesics in patients who suffered from primary liver cancer, and observed apitherapy’s role in patients with primary liver cancer pain, and provided a more safe and effective clinical treatment.MethodsAll60patients from the first Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, were divided into treatment group and control group,30cases in each group. Then we observed Karnofsky (KPS), Performance Status (PS), red blood cells (RBC), white blood cells (WBC), platelet (PLT), alanine aminotransferase (ALT), aspertate aminotransferase (AST), HBV-DNA, Hamilton Depression Scale (HAMD), visual analog scale (VAS), and so on. All data were analyzed by SPSS17.0.Results(1) There was no significant difference in curative effect after three courses between treatment group and control group (P>0.05) while there was a significant difference in curative effect after24h of three courses (P<0.05).(2) There was a significant difference in visual analog scale between treatment group and control group(P<0.05).(3) There was no significant difference in the onset time of analgesia between treatment group and control group (P>0.05) while there was a significant difference in Duration of analgesia between treatment group and control group (P<0.05).(4) There was no significant difference in Hamilton Depression Scale before treatment between treatment group and control group (P>0.05) while there was a significant difference in Hamilton Depression Scale after treatment between treatment group and control group (P<0.05).(5) There was no significant difference in RBC before treatment between treatment group and control group (P>0.05), and there was no significant difference in RBC after treatment between treatment group and control group (P>0.05).(6) There was no significant difference in PIT before treatment between treatment group and control group (P>0.05) while there was a significant difference in PLT after treatment between treatment group and control group (P<0.05).(7) There was no significant difference in WBC before treatment between treatment group and control group (P>0.05) while there was a significant difference in WBC after treatment between treatment group and control group (P<0.05).(8) There was no significant difference in AST before treatment between treatment group and control group (P>0.05) while there was a significant difference in AST after treatment between treatment group and control group (P<0.05).(9) There was no significant difference in ALT before treatment between treatment group and control group (P>0.05) while there was a significant difference in ALT after treatment between treatment group and control group (P<0.05).(10) There was no significant difference in HBV-DNA before treatment between treatment group and control group (P>0.05) while there was a significant difference in HBV-DNA after treatment between treatment group and control group (P<0.05).Conclusion1.The two methods of treatment to primary liver cancer all have certain curative effect.2. The effect of analgesics with apitherapy group for primary liver cancer pain is better than simple analgesics group, and the former can significantly relieve the depressive state of patients.3. Analgesics with apitherapy treatment group can significantly improve WBC, PLT, ALT, AST, HBV-DNA while simple analgesics group havs no effect on those sides.