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System Evaluation Of Chronic Gastritis Treated By Chaihu Shugan Powder

Posted on:2012-11-23Degree:MasterType:Thesis
Country:ChinaCandidate:L Y LinFull Text:PDF
GTID:2154330335468172Subject:Chinese medicine
Abstract/Summary:PDF Full Text Request
ObjectiveUsing evidence-based medicine methods on chronic gastritis treated by chaihu shugan powder for system evaluation, evaluation of their effectiveness and safety, so as to provide a measure of chronic gastritis treated by chaihu shugan powder evidence-based medicine, clinical applications and provide a basis for further study.MethodsSubject:domestic published, study on curative effect of chronic gastritis treated by chaihu shugan powder randomized controlled documents. Document source:electronic databases including Chinese biomedical literature database (CBMweb), PubMed result NCBI full text periodical database, Chinese periodical full-text database (CNKI), hand searching relevant journals professional information. Up to January 1979.Inclusion criteria:study design as randomized controlled trials or quasi-randomized controlled trials, whether or not blinded; trial included a parallel placebo control group, triple therapy or other medicine, non-specific treatment and other traditional Chinese medicine treatment; chronic gastritis age, gender, case open source, there are clear diagnostic criteria; mainly used CHSGS treatment of chronic gastritis; with one or a more effective evaluation of the following indicators:cure rate and total effective rate, the total efficiency, Helicobacter pylori negative rate, pathological improve the situation, adverse reactions, the incidence of gastric cancer. Clinical studies on the characteristics of descriptive analysis, such as general literature, disease inclusion and exclusion criteria, criteria of efficacy, randomization, sample size, balance between the two groups compared to the use of blinding, treatment methods, statistical methods, follow-up, exit and lost, recording and analysis of adverse reactions, etc., based on the evaluation form to calculate the percentage of all the circumstances, and descriptive analysis. Test included studies conducted by Jada Methodological Quality Assessment Scale. Application ochrane Collaboration Meta-analysis provided RevMan4.2; and funnel plot analysis with publication bias.ResultsTotal of chronic gastritis treated by chaihu shugan powder seized documents of 295 articles, be met the inclusion criteria of the RCT literature 17 articles. Literature quality evaluation by Cochrance Center Jadad score, 16 article for 1 min,1 article 2, shall belong to the low quality of the research literature.17 articles in the RCT, using clear diagnostic criteria of traditional Chinese medicine and Western medicine 7 articles, there are 15 articles of TCM diagnostic criteria, clear diagnostic criteria of Western medicine has 9 articles.8 article with clear inclusion criteria, an explicit exclusion criteria of literature has 9 articles, all documents with clear clinical criteria.16 document only refers to "random" words,1 article uses a random number table.15 between the article on equilibrium analysis and comparison of the statistics,1 comparison between the article balance is simple only described as "two sets of comparable". Only 1 article uses a single-blind method. No 1 article shows sample size estimation, distribution of stealth.17 article account of the statistical methods, only 1 article to the statistics of a specific size; 1 article record adverse; all documents are free to exit and loss to follow-up of case records and analysis. Chronic gastritis treated by chaihu shugan powder (total effective) effect of value (than the effect of the treatment and control groups) OR=2.53,95% interval (1.23,5.19).ConclusionThrough Meta analysis CHSGS effective treatment of chronic gastritis. But if there are more high-quality treatment of chronic gastritis CHSGS the research literature that offer, will make of this study demonstrated the causal relationship between strength and look forward to a full randomized controlled trials of high-quality content to the clinical literature on the study The results further confirmed.
Keywords/Search Tags:Chronic gastritis, Chaihu shugan powder, system evaluation, evidence-based medicine
PDF Full Text Request
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