Research The Effects And Mechanisms Of YiQiWenYangHuoXueFa On Patients With Chronic Heart Failure

Objective:Research the effects and mechanisms of YiQiWenYangHuoXueFa on patients with chronic heart failureMethods This research reference the diagnostic criteria based on Western medicine and Chinese medicine. Research selected 150 patients with chronic heart failure as the observation object, whose syndrome type are xinyangkuixu, xinxueyuzhu. The subjects were randomly divided into 2:1 in the treatment Group (100 cases), and the control group (50 cases). The treatment group was given Xinyangpian and traditional Chinese medicine decoction of YiQiWenYangHuoXueFa basis of Western medicine treatment. The control group was just given western medicine treatment. After two week's treatment, the research observed the change of general project (heart rate, blood pressure, breathing etc.), the points Minnesota living with heart failure questionnaire, NYHA classification, TCM syndrome score, RDW, PRA, Angâ…¡, ALD, BNP, etc. Using SPSS11.5 to statistics and analysis the results.Result Ues paired t test to compare The treatment group and control group. The results suggest that red blood cell distribution width between the two groups, B-type natriuretic peptide, renin, angiotensinâ…¡statistically significant difference between before and after treatment, (P<0.05), Aldosterone in both groups before and after treatment was no significant difference (P> 0.05), heart rate before and after treatment between the two groups was statistically significant (P<0.05), but respiration, blood pressure before and after treatment was no significant difference between the two groups(P>0.05). Between the two groups before and after treatment of Chinese medicine symptom scores between the two groups, the Minnesota Points significantly different (P<0.05), while prompt and effective treatment rate of heart function than the control group (67%,52%)Comclusion Chinese medicine treatment (Xinyangpian+ traditional Chinese medicine decoction of YiQiWenYangHuoXueFa) with the Western basic treatment, can significantly reduce red blood cell distribution width, B-type natriuretic peptide, renin, angiotensinâ…¡and the TCM symptom scores., points and Minnesota Improve heart function, and basic treatment than Western medicine alone is more effective, no significant increase in adverse reactions, can be considered to be clinically safe and effective drug.