| ObjectivesChronic kidney disease (CKD) is caused by multiple complicated reasons, with the course of the disease over 3 months, slow gradual progress and insidious pathogenesis, which is prone to miss the best time to treat at the early phase. Chinese medicine (TCM) has the obvious therapeutic efficacy in alleviating the symptoms, protecting the residual renal function (RRF) and delaying the progress of CKD, which to some extent, could improve the quality of life (QOL) of the patients. In the present dissertation, moxibustion therapy was added during the treatments, which was to further explore a better comprehensive treatment of TCM in delaying the natural progress of CKD, delaying the phase before the kidney dialysis and better improving the QOL of the patients.Methods52 cases of CKD were enrolled and randomly divided into the treatment group(moxibustion intervention)and the control group(non-moxibustion intervention), with 26 cases in each group. In the treatment group, all the patients were guided to have moxibustion at Zhongwan (RN 12) and Guanyuan (RN 4) by themselves,15 minutes each point each time, once a day for 3 months or more. In the control group, the routine integration of Chinese and western medicine were applied. Before and after the treatments, the serum was tested and the TCM symptom scoring scale was evaluated. After the treatments, all the data were statistically analyzed and the therapeutic efficacy was assessed.Result1. In the treatment group, the symptom scores before the treatments were 7 (6,9) and 5.5(4,6.25) after the treatments, with significant difference between pre- and post-treatments (P<0.05); in the control group, the symptom scores before the treatments were 7(6,8) and 6(4,7) after the treatments, with significant difference between pre- and post-treatments (P<0.05), which indicated that both the two therapies were effective in treating CKD.2. In the treatment group, the syndrome scores of TCM before the treatments were 5(4,6) and 3.5(3,5) after the treatments, with significant difference between pre- and post-treatments (P<0.05); in the control group, the syndrome scores of TCM before the treatments were 5(4,6) and 5(3,6) after the treatments, with significant difference between pre- and post-treatments (P<0.05), which indicated that both the two therapies were effective in treating CKD.3. In the treatment group, serum creatinine before treatments was 124.70±25.13umol/L and 117.23±25.77umol/L after treatment, with significant difference between pre- and post-treatments (P<0.01); in the control group, serum creatinine before treatments was 124.15±30.67umol/L and 119.61±32.20umol/L after treatment, with significant difference between pre- and post-treatments(P<0.05);which indicated serum creatinine decreased after the two therapies.4. With the therapeutic efficacy, in the treatment group,1 case was obviously effective,12 were effective and 13 were stable, with the total effective rate as 96.1%; in the control group,4 case was effective,17 were stable and 5 were ineffective, with the total effective rate as 80.7%. With the statistical management, there was significant difference between the two groups (P<0.05), which indicated that TCM plus moxibustion could enhance the clinical therapeutic efficacy in the treatment of CKD.5. With the TCM syndrome therapeutic efficacy evaluation, in the treatment group,16 cases were effective and 11 were ineffective, with the effective rate as 61.5%; in the control group,8 were effective and 18 were ineffective, with the effective rate as 30.7%. There was significant difference between the two groups, which indicated that moxibustion could enhance the therapeutic efficacy of TCM in treating the main symptoms.Conclusion1. Moxibustion and TCM treatment could stably relieve the symptoms of CKD.2. Moxibustion and TCM treatment could improve the syndrome scores of TCM.3. Moxibustion plays an important role in strengthening the therapeutic efficacy in the TCM treatment of CKD. 4. Moxibustion is of significance in the treatment of CKD, which is worthy of being further popularized for application to patients.
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