The Correlation Analysis Between Polysomnography And Neurotransmitter Of Sleep Disorder In Soldiers In Diqing Plateau

[Objective] To understand sleep structure and the change of the subjective and objective sleep quality in soldiers in Diqing plateau,and the differences between objective and subjective sleep quality, to explore the correlation between polysomn-ography and neurotransmitter of sleep disorder in soldiers in Plateau.[Methods]A total of 242 male soldiers were randomly selected from four companies in Diqing (elevation 3700m) and the artillery unit stationed in Kunming (elevation 1800m); Self-made questionnaire, Pittsburgh Sleep Quality Index (PSQI) Scale, Hamilton Depression Rating Scale (HAMD) and Hamilton Anxiety Scale (HAMA) conducted a questionnaire survey; Sleep disorders without anxiety and depression in Diqing plateau and Kunming were selected according to the above standards, Sleep normals without anxiety and depression in Diqing plateau and Kunming were selected according to the above standards; All the four groups were tested by polysomnography and Encephaloflutuograph.[Results]1. The prevalence of sleep disorders(47.69%)in plateau forces was significantly higher than that of Kunming(37.50%), the difference was statistically significant (p<0.01). Sleep quality score of plateau forces was higher than that of Kunming.2. In the case of the total recording time was no significant difference (p>0.05), the plateau sleep disorder group of non-rapid eye movement (NREM)â… prolonged,â…¡stage,â…¢+â…£of and rapid eye movement (REM) period shortened, sleep latency. awakening, the number of total arousal prolonged sleep, increase conversions, reduce total sleep time, sleep efficiency decreased, compared with sleep disorders in Kunming, the difference was statistically significant (p<0.05); The average SaO2 in awaking and sleeping, the maximum SaO2 in sleeping in sleep disorders of plateau were significantly lower than the average sleep disorder group in Kunming (p<0.05).3. Objective and subjective sleep latency, sleep disturbance group, subjective and objective sleep time, subjective and objective efficiency in plateau group were different(P<0.05).There were also differences in Kunming group(p<0.05).4. The difference between objective and subjective sleep latency, the difference between objective and subjective sleep time, sleep efficiency difference between objective and subjective sleep disturbance in plateau group was statistically significant (p<0.05), comparing with Kunming group, and the differences was larger than Kunming group.5. Nationality (OR 0.260,95%CI 0.096-0.703), marital status(OR 0.024,95%CI 0.002-0.361), anxiety (HAMA> 14)(OR5.570,95%CI1.879-17.562),were independent predictors leading to sleep disturbance in high altitude group(PSQI>7).Among them, nationality, marital status were protective factors of sleep disorders in the plateau; and anxiety was a risk factor for sleep disorders. There wasn't independent predictors and significant risk factors, leading to sleep disorders in Kunming group(PSQI>7).6. By the correlation analysis between PSG objective sleep monitoring indicators and neurotransmitter changes in the plateau of sleep disorders, we found REM period and Ach was positively correlated (r=0.431), and 5-HT were positively correlated (r=0.025), total sleep time and GABA was positively correlated (r=0.666), sleep, number of conversions and 5-HT was negatively correlated (r=-0.016) and NE was positively correlated (r=0.048).[Conclusion]1.The prevalence of sleep disorders in plateau forces was significantly higher than that of Kunming forces. Sleep quality score of plateau forces was higher than that of Kunming.In the case of the total recording time was no significant difference (p>0.05), the plateau sleep disorder group of non-rapid eye movement (NREM)â… prolonged,â…¡stage,â…¢+â…£of and rapid eye movement (REM) period shortened, sleep latency, awakening, the number of total arousal prolonged sleep, increase conversions, reduce total sleep time, sleep efficiency decreased, compared with sleep disorders in Kunming, the difference was statistically significant (p<0.05); The average SaO2 in awaking and sleeping, the maximum SaO2 in sleeping in sleep disorders of plateau were significantly lower than the average sleep disorder group in Kunming (p<0.05).2. Objective and subjective sleep latency, subjective and objective sleep time, subjective and objective efficiency were different in plateau group and Kunming.3.The risk factors the affecting subjective sleep disorder PSQI in plateau were anxiety.4.Objective sleep monitoring indicators PSG and neurotransmitter changes were related in plateau soldiers of sleeping disorder, showing REM period and Ach was positively correlated with 5-HT was also positively correlated, total sleep time and GABA was positively related to sleep conversions and 5-HT was negatively correlated, also with NE were positively correlated.