| Ischemic cerebral stroke refers to various causes of brain blood supply obstacles, make a part of brain tissue happen ischemia broadened necrosis. With the continuous development of modern medicine, ischaemic stroke mortality rates continue to drop, but its recurrence risk is increased. Recent epidemiological studies says China each year about 150 to 200 million cases of cerebral apoplexy, at present our country's existing cerebrovascular disease patients have over 700 million people, of whom 70% for ischemic stroke, quite a proportion of patients with multiple risk factors, is at risk of recurrent stroke individuals[1].To have different patients with risk of recurrent stratified. Develop individualized, targeted treatment options, early to take effective preventive measures is to prevent the recurrence of ischemic cerebral stroke in the key.To Ischemic cerebral stroke recurrence risk assessment, domestic and foreign scholars have been long-term exploration, many studies have established effective and feasible risk assessment method, and gradually applied to prevent practice. The Essen Stroke Risk Score(ESRS)applies to exclude af patients caused Ischemic Stroke. So far, it has been in European countries stroke crowd validity research many times. Research results show that either in stable condition for the outpatient clinic of ischemic stroke patients, or hospitalization of patients, ESRS can more reasonable forecast the ischemic stroke and compound in cardiovascular events happen again risk. This Score not only easy to use, but also for ischemic stroke was confirmed recurrent prediction, it can be effective and feasible for the risk of ischemic stroke in patients with stratified tools[2]. Its receive a variety of ischemic stroke risk factors, but not including carotid atherosclerosis and the degree of carotid stenosis. Recent studies show that the occurrence of carotid atherosclerosis and carotid artery stenosis is an important cardiovascular disease risk factors ,also be the important risk factors for ischemic stroke relapse independent risk factor.CDFI are the important non-invasive detection methods of hemodynamic assessment, indicators for monitoring blood flow velocity and blood flow spectrum and changes in lumen can reflects the degree of blood vessels narrow, plaques and hemodynamic changes. Therefore, it carotid atherosclerosis in patients with ischemic cerebral stroke and the degree of stenosis can play a very good assessment of the role, and it is a simple, easy, economical, safe, non-invasive advantages.In this study ,we choose 507 patients with ischemic cerebral stroke in China Japan union hospital of JILIN university from March 2008 to March 2010, Which once again due to recurrence of ischemic cerebral stroke patients admitted 82 patients. All patients first clinical data on admission,have already completed the Color Doppler Flow Imaginging. According to the first admission for patients with clinical data of ESRS score, and record the patient's Color Doppler Flow Imaginging change. Application of ROC curves to determine ESRS recurrence of ischemic cerebral stroke risk prediction value. And apply it to determine ESRS United CFDI recurrence of ischemic cerebral stroke risk prediction value. The recurrent group and non- recurrent group compared with ESRS score. ESRS≥3 points and the ESRS <3 points compared with CFDI in the recurrent group. Recurrent group and non- recurrent group compared with CFDI. Recurrence of ischemic cerebral stroke risk factors in 2 years using logistic regression analysis. All of the data apply SPSS16.0 package for processing, x±s is applied for quantitative data, t test is applied in the test of significance of mean number, frequency distribution using X2 test. Using ROC curve to evaluate the clinical value of ESRS and Logistic regression model for multivariate analysis. The results indicate that age, high blood pressure, diabetes, previous myocardial infarction, other cardiovascular disease, peripheral arterial disease, smoking, history of ischemic stroke / TIA history, carotid plaque and stenosis were recurrent ischemic stroke risk factors.Studies have shown that: Recurrent group and non- recurrent group scores are 3.21±0.61,2.23±0.39;the ESRS scores of Recurrent group are higher than the non- recurrent group. (P<0.05)there is 68 patients with ESRS≥3 points in recurrent group(82.9%),and there is 294 patients with ESRS≥3 points in non- recurrent group(69.2%). The proportion of patients with ESRS≥3 in recurrent group significantly higher than non- recurrent group. Recurrent group ESRS≥3 points, CFDI examinations showed accompany by carotid plaque were 53 patients (77.9%)Recurrent group ESRS <3 points, CFDI examinations showed accompany by carotid plaque were 8 patients(57.1%)The proportion of patients in recurrent group accompanied by ESRS≥3 points and carotid plaque is higher than the ESRS <3 points patients.In the recurrent group CFDI examinations showed carotid plaque in patients with 61 patients (74.4%), 28 patients with carotid artery stenosis (34.1%); In the non-recurrent group CFDI examinations showed carotid plaque in patients with 247 (58.1%), 73 patients with carotid artery stenosis (17.2%), The proportion of patients in recurrence group with carotid artery plaque or stenosis are higher than the non-recurrent group (P <0.05). Recurrence of ischemic cerebral stroke risk factors in 2 years using logistic regression analysis.To sum up, the following conclusions can be drawn: The Essen Stroke Risk Score (ESRS) and Color Doppler Flow Imaginging (CFDI)changes in recurrence of ischemic stroke risk have predictive value, and the better the predictive value of their combination. Ischemic cerebral stroke patients accompanied by carotid artery plaque,carotid stenosis and ESRS≥3 points are more likely to recurrent. Age,hypertension, diabetes, previous myocardial infarction, other cardiovascular disease, peripheral arterial disease, smoking, history of ischemic stroke / TIA history, carotid plaque and stenosis were recurrent ischemic stroke risk factors.
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