The Relationship Between ApoB/apoA1 And The Severity Of Coronary Artery Atherosclerotic Lesion

Objective:The prupose of this research was to compare the blood serum apoB,apoAl and apul//upoAI Of coronary Iesions group and normal control group,explore apoB,apoAl and apoB/apoAl With coronary Icsions and relationship Of clinical significance.Andforthe lipid treatment ofcoronary disease provide certain referrence.Methods: With"bosom frowsty.chest pain"income courtyard of the suspected patients 304cases(male 22 1 cases.female 83 cases,age 51 69±8.9 years old, each patient underwent coronaryangiography,and according to the imaging results and the cumulative lesions count is divided intonormal control group 75 cases,a single lesion 67 cases.double teams group 72 cases.three lesions group branch and multivessel disease group 90 cases In combination with Gensini rating criteria ofpatient each coronary lesions scientifically and quantitative evaluation.All in all patients intomorrow morning fasting extraction venous blood after admission on that dav_send mga determineils total cholesterol(TC)(mmol/l),triglycerides(TG)(retool/l).high—density lipoprotein(flDL—mmol/I)(c),apolipoprotein B(apoB)(g/I)and apolipoprotein AL(apoAI)(g/I).10w--density lipoprotein (DL-C)=(TC-HDL)1-C-TG;/2.2)。Results(1)304 suspected coronary heart disease patients.according tO results ofthosediagnosed coronary angiography 229 example,patients with normal controls 75 cases.(2)Coronary lesions in the group TC,LDL—C and coronary lesions Gensini integral positivelycorrelated.hdl-C , apoAl with coronary lesions Gensini integral negatively correlated,apoB,apoB/TG apoA 1 Gensini integral with coronary lesions not seen obvious correlation(3)Coronarylesions in the group TC,LDL-C and coronary lesions was positively associated with apoAl countscorollary lesions count negatively correlated,TG,hdl-C,apoB,apoB/apoAI with coronary lesionscounts not seen obvious correlationConclusion: Coronary heart disease patients with coronary lesions oflipid index has certaincorrelation degree . including apolipoprotein with coronary lesions is closely,related to apoAldegree of coronary lesions the predictability of the strongest.