Intervening Research Of Method Of Reinvigoration And Removing Toxicity (RRT) On The TNF-α And ET In Early-Stage Diabetic Nephropathy

Objective:To observe the clinical efficacy of reinvigoration and removing toxicity(RRT) in treatment of early-stage diabetic nephropathy, and to discuss the clinical significance of TNF-αand ET in the course of early-stage diabetic nephropathy.Methods: After one month of the basal treatment for patients with early-stage DN, the 60 cases of patients who measured up the test standard were divided into two groups randomly. The patients in control group were treated continuously with basal treatment including diabetic education, lowering glycemia and blood pressure et,al.While the treatment group were added tranditional Chinese medicine of reinvigoration and removing toxicity on the basis of basal treatment.The period of treatment is one month.The results of clinical symptoms, urinary albumin excretion rate(UAER), TNF-αand ET of before and after treatment were compared.Results:Treatment group was superior to the control group in improving the clinical symptoms, lowering albuminuria, inflammation marker, improving renal function abviously.There was no adverse reactions in the course of treatment. Conclusions:The method of RRT can improve the clinical symptoms of early-stage diabetic nephropathy,low the expression of inflammation marker,the elimination of albuminuria,and postpone the process of renal function damaging of early-stage diabetic nephropathy.