Explore The Intrauterine Disorders In Female Infertility And Sterility

Objective To explore the intrauterine disorders that leads to infertility and sterility in women. To explore the difference the main cause of the three types of infertility. To provide clinical data for further searching for the relations between infertility and the intrauterine causes.Methods From March 1993 to March 2008, a total of 2077 patients with infertility received hysteroscopic examination at Nanjing Drum Tower Hospital. Among the patients, 531 were diagnosed with intrauterine abnormalities including primary infertility in 172 (32.4%) cases, secondary infertility in 315 cases (59.3%), and sterility in 44 (8.3 % ). The clinical data of these patients were analyzed retrospectively.Results The most common cause of infertility and sterility in the patients was intrauterine adhesion (231 cases, 43.5%), followed by uterine deformities (152, 28.6%) and endometrial polyps (88,16.6%). In the primary infertility group, the most common reason was endometrial polyps, which was detected in 38.4% of the cases(66/172). The rate was significantly higher than that in the secondary infertility group (6.0%, 19/315) and sterility group (6.8%, 3/44)(χ~2=80.7630,P =0.000,χ~2=16.0463,P =0.000). While in the secondary infertility group, intrauterine adhesion was detected in most of the patients (60.6%, 191/315), that was significantly more than that in the sterility and primary groups (25.0%, l1/44,χ~2=19.9232, P =0.000,χ~2=86.0747, P =0.000 and 16.9%, 29/172,χ~2=86.0747, P =0.000, respectively). For the patients with sterility, the disease was caused by uterine deformities mostly (65.9%, 9/44), which is significantly different from the other two groups (secondary group: 25.1%, 79/315,χ~2=30.5994, P=0.000; primary group: 25.6%,χ~2=25.4673, P=0.000).Conclusion The most common cause of infertility and sterility in the patients is intrauterine adhesion , followed by uterine deformities and endometrial polyps. The major causes of primary infertility, secondary infertility, and sterility are endometrial polyp, intrauterine adhesion, and uterine deformities respectively. uterine deformities comprise Uterine Septum mainly...