Increase The Smooth Liquid Festival Soup Treat Experimental Study Of KOA

Objective:To establish a rabbit model of knee osteoarthritis, contrast with by increasing the smooth liquid festival soup and the immortal bone luxuriant growth capsule,section by increase the smooth liquid festival soup on the treatment of knee osteoarthritis,which can show that yin and blood and collaterals protection in the treatment of knee osteoarthritis and aging joints have a certain effect.Methods:The experiment was 2010-3/4 in the People's liberation Army NO.208 Hospital animal laboratory In addition to the normal group than the other groups according to intra-articular injection of papain established rabbit model of knee osteoarthritis,7 days were randomly selected model group 2 rabbits, take the right knee did HE staining to show that the model was successful. After the modeling of each group were fed rabbits, in which C group irrigation Xianlinggubao capsule 175mg, D group Run-section increase in liquid filling soup 10ml, A, B groups were irrigated with normal saline, twice daily. Free feeding all the animals were sacrificed after 4 weeks.â‘ shoot right knee knee X-ray observation of the macro-structure, including soft tissue, joint space, joint surface changes and the presence of osteophyte formation.â‘¡The film cut knee surgery, general observation of cases of synovial and cartilage.â‘¢The articular cartilage, do biopsy (HE stain) of treatment, morphological changes of articular cartilage.Resuts:â‘ through the normal knee compared with model group, model group Xray shows slight joint space narrowing,subchondral bone density inequality shows that the model was successfulâ‘¡articular cartilage by HE stain, you can see C group and D group of articular cartilage morphology and B were significantly different than (P <0.05), while no significant difference between the two (P> 0.05).Conclusion:Increase the smooth liquid festival suop in the treatment of osteoarthritis and Xianlinggubao capsule, but no significant difference.Both can promote cartilage matrix synthesis, inhibition of cartilage matrix degradation, thereby promoting repair of injured joints. Description Yin Huayu Tongluo protection in the treatment of osteoarthritis and aging joints have a certain effect.