The Analysis Of Related Factors Of The Twin Premature Infants With Brain Injury

ObjectiveTo explore the forms, features in MRI and related factors of brain damage in the twin premature infants.MethodsThe study was retrospectively performed on 92 pairs (184 cases) premature infants who accepted hospitalization in neonatal ward of our hospital from March 2007 to March 2010. Both twins according to the first magnetic resonance imaging findings classify to three groups. A group:both twins with brain damage; B group:one of the twins with brain damage; C group:both twins without brain damage. Investigate related factors of the brain damage in premature infants:gestational age, birth weight, mother factors (maternal age, maternal infection during pregnancy, maternal diabetes during pregnancy, etc.), obstetric factors (fertilization methods, means of delivery, premature rupture of membranes, etc.), postnatal complications (hyperbilirubinemia, hypogly-cemia, infection, etc.). Compared and analysed. A, B, C groups.ResultsThere is 28 pairs in group A (both twins with brain damage), and 24 pairs in group B (one of the twins with brain damage), and 40 pairs in group C (both twins without brain damage). Gestational age in the group A, B & C was not statistically significant; Birth weight in the group A, B & C was statistically significant. P values of vaginal delivery,1 min Apgar score<7 (asphyxia), early infection among grops A, B, C were <0.05, implied they are different among the three groups.ConclusionIt is similar to single preterm,cerebral white matter injury is the major forms of MRI in twin preterm with brain injury. Smaller weight of the twin preterm more likely to fall in brain injury.Vaginal delivery, neonatal asphyxia and early infection may be the factors relate to. brain damage of the twin premature infants.