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The Study Of Lower Extremity Arterial Disease In Patients With Essential Hypertension With Color Doppler Ultrasound

Posted on:2011-11-27Degree:MasterType:Thesis
Country:ChinaCandidate:F L MengFull Text:PDF
GTID:2144360305954602Subject:Clinical Medicine
Abstract/Summary:PDF Full Text Request
Essential Hypertension(EH) is the common and frequently occurring illness in the middle-aged and old people. The main hazard of EH is atherosclerosis and the function damage of important organs, a serious illness which hazard to human beings. First of all, EH lead to the changes in arterial structure and function, and then hemodynamic disturbance occurred, and the vital organs damage of the heart, brain developed at the same time as the progress of hypertension. Therefore, the strengthening study of the artery structure and function in hypertension patients has important clinical value..Color Doppler ultrasound for its simple, real-time, accurate, has become the preferred method to examination atherosclerosis, and the technology can early detection of atherosclerosis, and to understand the features of development and changes in atherosclerosis, and to find characteristics of peripheral vascular lesions in hypertensive patients in order to provide the basis for its treatment.Objective:Detected peripheralartery disease of hypertension patients with two-dimensional and Color Doppler ultrasound. Respectively, analysis the artery morphology and hemodynamics, including disease characteristics, severity, blood flow, blood parameters and blood flow changes in the spectrum shape. Investigation ultrasound diagnosis of lower limb atherosclerosis, in order to clear the influence of hypertension on lower limb artery..Methods:90 patients of EH as the research object, divided into 3 groups according to the standard classification of hypertension, and 30 cases of every grade,And select 30 for the control group..All individuals who underwent lower limb ultrasonography, observed pairs of femoral artery, popliteal artery, anterior tibial artery, posterior tibial artery, dorsalis pedis artery. Record the thickness of IMT, plaque size and echo, calculate Crouse points, observate the nature of the stenosis degree, record systolic blood flow velocity and spectral characteristics.Results: (1)The lower extremity arteries of hypertensive patients in every level shows ultrasonic features; in two-dimensional ultrasonography, IMT thickness, detection rate of plaque in each group of EH were significantly different compared with the control group(P <0.05). (2)The Crouse points and narrow classification can be used as the degree of atherosclerosis, each group of hypertension was significantly different compared with the control group(P<0.05), the higher blood pressure level , the more Crouse points, and significantly different (P <0.05)..Among the three group of hypertension, stenosis of gradeâ…¡, gradeâ…¢gradually increased with the blood pressure level, which were significantly different (P <0.05). (3) The hemodynamics can reflect the arterial lesions to a certain extent, a high blood pressure and 2 high blood pressure compared with control group, Vmax, RI, PI was no significant difference (P <0.05). 3 hypertension and the control group, a relatively high blood pressure and 2 high blood pressure, Vmax, RI, PI were significantly different (P <0.05). (4) systolic blood pressure, pulse pressure as risk factors for atherosclerosis play an important role, and the occurrence is directly related to atherosclerosis and there were positive correlation.Conclusions: The lower extremity arterial structure and function of hypertensive patients have changed, so hypertension is a significant risk factor for atherosclerosis.The degree of blood pressure is different ,and the arterial lesions is different.Application of Color Doppler ultrasound may evaluate function and structure of Lower extremity arterial disease,and related.to the classification of hypertension .
Keywords/Search Tags:essential hypertension, Lower extremity atherosclerosis, Color Doppler ultrasound
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